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It is produced by the strain of Streptomyces distallicus NCIB 8936. It has the activity against gram-positive bacterium, mycobacterium, dermatophyte and Trichophyte. It has inhibitory effects on solid tumors such as Epstein-Barr ascites carcinoma, sarcoma 180, Walker 258, oberling-Guerin osteoma, and also inhibits vaccinosis virus, herpes simplex virus, adenovirus, and mouse hepatitis virus in cell culture.

It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. Dynemicin A has a strong killing effect on a variety of tumor cells at Pg/mL level. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells.

It is produced by the strain of Streptomyces echinatus. It has the activity of anti-gram-positive bacteria and vaginal trichomonas, and also has the effect on influenza virus and sarcoma 180 cells in vitro.

Illudin M is a natural sesquiterpene agent with strong anti-tumour activity.

a potent anti-fungal antibiotic. Leptomycin A is a highly specific inhibitor of export protein CRM1.

Naphthomycin A is a macrolide (Ansa family) antibiotic produced by strains such as Str.collinus Tv105, Str. galbus subsp. griseosporeus Tv 353, Str. diastatochromogene, Str. sp. Y83 40369. It has activity against gram-positive bacteria and fungi.

Mithramycin A is an antineoplastic antibiotic produced by Streptomyces plicatus. Mithramycin A is a polymerase inhibitor that binds to GC rich sequences located in the minor groove of DNA.

Netropsin is isolated from Streptomyces netropsis as a basic polypeptide. It can specific bind to A-T areas of DNA that is very useful to genetic research. Netropsin can disrupt the cell cycle, prolonging G and arresting in G. Netropsin has antibiotic and antiviral activity. It has been shown that Netropsin is active against Gram-positive and Gram-negative bacteria.

Oleandomycin is a 16-membered macrocyclic lactone originally isolated from Str. antibioticus. It has broad spectrum antibacterial activity.

It is produced by the strain of Str. pactum var. pactum NRRL 2939. It is a cyclopentane and cyclohexane derivative antibiotic. It has anti-bacterial, virus, tumor activity.

It is produced by the strain of Streptoverticillium verticillum 843-1. It's a heteropeptide antibiotic. It has anti-gram-positive bacteria, negative bacteria and mycobacterium effects. The therapeutic index of the complex for Solid Adenocarcinoma and Sarcoma-180 are 16. The therapeutic index of Ehrlician ascites cancer is 4-8. It acts an antibiotic originally, an anticancer agent and a selection agent for transformed algae, protista, animal and fungal cells.

Tallysomycin A is a glycopeptide antibiotic produced by the rare actinomycete No. E 465-94. It has anti-gram-positive bacteria and gram-negative bacteria and fungi activity. It can induce lysogenic E. coli W1709 (A) to release phage.

Tunicamycin, a mixture of homologous nucleoside antibiotics, has been used to study the effect of N-linked glycosylation of human proton-coupled folate transporter (HsPCFT) in HeLa cells. Tunicamycin blocks the formation of N-glycosidic linkages by inhibiting the first step in glycoprotein synthesis. It exhibits a range of biological activities, including antimicrobial, antivirus, and antitumor effects. It is produced by certain bacteria, including Streptomyces lysosuperficus and Streptomyces chartreusis.

Bambermycin (flavomycin) is a complex of antibiotics obtained from Streptomyces bambergiensis and Streptomyces ghanaensis used as a food additive for beef cattle, dairy cattle, poultry and swine. The complex consists mainly of moenomycins A and C.

Pentostatin is an adenosine deaminase inhibitor isolated from Streptomyces and effective against cancer cell lines. Pentostatin is a purine nucleoside analog that irreversibly inhibits adenosine deaminase (Ki = 0.9 pM) and thus interrupts DNA synthesis in dividing cells. Pentostatin has been reported to display strong efficacy in the clinical treatment of hairy cell leukemia as well as relapsed chronic lymphocytic leukemia.

An unusual anthracycline produced by streptomyces nogalater var. Nogalater. It is a potent antibacterial and antitumor agent that interacts with DNA by intercalation.

Ramoplanin complex is a complex of three high molecular weight glycolipopeptide peptides, the chain length and the shape of the diketene lipid side chain are different. It inhibits cell wall biosynthesis through a mechanism different from vancomycin-related glycopeptide.

Kirromycin is an antibiotic originally isolated from Streptomyces. It was shown to inhibit protein biosynthesis via acting on elongation factor Tu (EF-Tu).

It is a mixture of eight cationic cyclic decapeptides antibiotic produced by bacillus brevis. It has a broad spectrum of antimicrobial activity against gram-positive and Gram-negative bacteria. Tyrocidine A is the major component of the tyrothricin complex which is used for treatment of topical infection. It acts by disturbing lipid bilayers of the bacterial cell membrane.

Berubicin has potential antineoplastic activity. Berubicin intercalates into DNA and interrupts topoisomerase II activity, resulting in the inhibition of DNA replication and repair, and RNA and protein synthesis.