Antibiotics

Clindamycin Phosphate is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM. It is usually used to treat infections with anaerobic bacteria, but can also be used to treat protozoal diseases, such as malaria. It is a common drug used to treat topical acne and can be effective against some methicillin-resistant Staphylococcus aureus (MRSA) infections. An impurity of Clindamycin.

A degradation product of tetracycline formed by acid-catalysed isomerisation of the dimethylamino-group at C4. It is an antibiotic and a cell selection agent. It exhibits little antibacterial activity.

Erythromycin B is a minor co-metabolite of erythromycin produced by fermentation of Saccharopolyspora erythreae. Erythromycin B exhibits broad spectrum antibiotic activity against Gram-positive and Gram-negative bacteria. An impurity of Erythromycin.

Antibiotic complex is produced by Streptomyces kanamyceticus Okami and Umezawa from Japanese soil. Kanamycin B is an aminoglycoside antibiotic with activity against gram-negative bacteria.

Marbofloxacin is a third generation fluoroquinolone antibiotic. Marbofloxacin exhibits high bactericidal activity against a broad spectrum of aerobic Gram-negative and some Gram-positive bacteria, as well as Mycoplasma spp.

It is a major component of the pseudomonic acid, an antibiotic complex produced by Pseudomonas fluorescens NCIB 10586. It is a carboxylic acid bacteriostatic/bactericidal antibiotic.

Oxacillin sodium monohydrate is a semi-synthetic antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.

It is the second of the broad-spectrum tetracycline group of antibiotics to be discovered. Oxytetracycline works by interfering with the ability of bacteria to produce essential proteins. It is an antibacterial isolated from the elaboration products of the actinomycete, Streptomyces rimosus.

It is a semi-synthetic antibiotic of the rifamycin group. It is an inhibitor of bacterial RNA polymerase and has antibacerial activity.

Roxithromycin is a semi-synthetic macrolide antibiotic that inhibits bacterial cell growth and replication. It is used to treat respiratory tract, urinary and soft tissue infections.

An aminocyclitol antibiotic similar to aminoglycosides.

(+)-ar-Turmerone, a kind of aromatic compound, is a natural antibiotic used as an anti-tumor and immune-activating agent. It is known as a potent anti-venom against snake bites. It has been reported to promote stem cell proliferation, is a factor in nerve cell regeneration and brain injury, and has anti-inflammatory properties. It is widely used in anti-aging, removing wrinkles, whitening and lightening spots, antibacterial and anti-inflammatory, and anti-sensitivity repair products, and is compatible with lotion cream formulas, gel formulas and water formulas.

A complex of depsipeptides produced by several fusarium species. the complex contains 4 major components: A, A1, B and B1 together with minor amounts of enniatins C, D, E and F.

A member of the paraherquamide family which causes a potent non-toxic paralysis of nematode. It is a fungal metabolite originally isolated from Penicillium charlesii with anthelmintic and insecticidal activities.

A macrocyclic antibiotic first isolated from S. sioyaensis with potent and selective antibacterial activity. It is a potent inhibitor of the oncogenic transcription factor, foxm1. It inhibits foxm1-induced cell growth on soft agar and selectively kills transformed but not normal cells in vitro.

A bacteriocin polypeptide antibiotic known as Lantibiotic. It is synthesized by Lactococcus lactis and produced by gram-positive bacteria to reduce competitive strain from other gram-positive bacteria.

An unusual tetronic acid, structurally related to kijanimicin, chlorothricin, saccharocarcin, tetrocarcin and versipelostatin. It is an antibiotic produced by Streptomyces. It has pronounced activity against antibiotic susceptible and resistant gram-positive bacteria including MRSA. It appears to target the phosphatidylinositide-3-kinase/akt signalling pathway.

An unusual tetronic acid, structurally related to kijanimicin, chlorothricin, saccharocarcin, tetrocarcin and versipelostatin. It is an antibiotic produced by Streptomyces. It has pronounced activity against antibiotic susceptible and resistant gram-positive bacteria including MRSA. It appears to target the phosphatidylinositide-3-kinase/akt signalling pathway.

It is a cyclic hexapeptide antibiotic first isolated from streptomyces sp. It was found to produce Salinamide A, an inhibitor of bacterial RNA polymerase. It has activity against S. aureus, S. pneumoniae and methicillin-resistant S. epidermidis.

A unique tetrasaccharide with six tiglate esters isolated from an unidentified amycolatopsis culture. It is a potent antitumour agent.