Antibiotics

It is an anticancer antibiotic first isolated from S. cyaneogriseus ssp. noncyanogenus (LL-F28249). It has more selective action against mammalian tumour cell lines than Oligomycin A, exhibiting only weak antifungal and nematocidal activity.

Streptochlorin is a metabolite originally isolated from Streptomyces sp. It exhibits antiangiogenesis, antiproliferation and antiallergic activities. It inhibits TNF-α-induced NF-κB activation.

A demethylated form of bleomycin A2 which is a major component in standard grade bleomycin. It is formed by heating bleomycin A2. It has high antimicrobial activity against mycobacterium smegmatis compared to bleomycin A2. It has a lower toxicity.

A salt form of Meropenem. It is a beta-lactam antibiotic in the carbapenem class.

A broad-spectrum beta-lactam antibiotic in the carboxypenicillin family.

It is produced by the strain of Micromonospora. One of three components of the gentamicin C complex which comprises approximately 80% gentamicin and exhibits the most potent antimicrobial activity.

It is produced by the strain of Bacillus sp. It is a highly purified form of bacitracin B1 and a compound present in standard grade bacitracin. It together with bacitracin B2 is slightly less active than bacitracin A.

It is produced by the strain of Bacillus polymyxa var. colistinus. Polymyxin E2 Sulfate is sulfate salt form of Polymyxin E2, which is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria.

It is produced by the strain of Bacillus polymyxa var. colistinus. Polymyxin E1 Sulfate is sulfate salt form of Polymyxin E1, which is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria.

It is produced by the strain of Pseudomonas Sp. It is one of the individual polypeptide components in polymyxin B sulfate. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram-negative bacteria leading to lysing of the cell.

It is produced by the strain of Pseudomonas sp. It is one of the polypeptide fractions in polymyxin B sulfate. Polymyxin B1 is an antibacterial compound. It has a high volume of distribution and longer elimination half-life in patients with multidrug-resistant gram-negative bacterial infection.

An antibacterial solution comprised of penicillin (10,000 units/ml), a beta-lactam, and streptomycin (10,000 ug/ml), an aminoglycoside in 0.9% NaCl.

It is a 16-membered macrolide antibiotic and a metabolite of Tylosin. It is also a precursor of Tilmicosin.

A highly purified form of tylosin A. It is a macrolide antibiotic, which is considered to be the major component of tylosin (comprises approximately 90% of tylosin). However, tylosins B, C and D contribute to the overall potency of tylosin.

A broad spectrum naphthoquinone antibiotic isolated from actinoplanes ianthinogenes.

A cyclic peptide antibiotic isolated from actinomadura sp. strain GE23077. It inhibits bacterial RNA polymerase.

It is an antibiotic produced by several species of streptoverticillium. It is a potent indirect inhibitor of phospholipase A2 by specifically sequestering phosphatidylethanolamine (PE). It has antiviral activity against herpes simplex virus type 1 KOS strain infection in Vero cells. It is also an immunopotentiator.

A degradation product of chlorotetracycline formed by acid-catalysed isomerisation of the dimethylamino group at C4. It exhibits little antibacterial activity.

Fosmidomycin is an antimalarial and antibiotic originally isolated from culture broths of bacteria of the genus Streptomyces and has been used as an inhibitor of DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis.

It is one of two components found in the glycopeptide antineoplastic antibiotic Bleomycin sulfate. Bleomycin sulfate is a chemotherapeutic agent used for the treatment of hodgkins lymphoma. It is isolated from the bacterium Streptomyces verticillus.