Antibiotics

Cephalexin hydrate is an semisynthetic cephalosporin antibiotic. It is effective against both gram-positive and gram-negative organisms.

Micafungin, also known as FK463, is a polyene antifungal medication used to treat and prevent invasive fungal infections including candidemia, abscesses and esophageal candidiasis. In a mouse model of septic A. fumigatus infection, although non-treated mice survived for a maximum of only 6 days, the survival rate of micafungin-treated mice (0.1 mg kg-1) increased to 20%, while the survival rate of mice treated with a combination of micafungin (0.1 mg kg-1) and KB425796-C (32 mg kg-1) increased to 100% during the 31-day post-infection period.

Cefazolin sodium, derived from 7-amino-cephalosporanic acid, is a semi-synthetic, first-generation cephalosporin antibiotic.

Cefamandole sodium is a second generation cephalosporin antibiotic.

Tilmicosin phosphate, an antibiotic, has been commonly used as a veterinary drug against ovine respiratory disease for bovine and ovine.

Cefoxitin is derived from cephamycin C, a semi-synthetic, broad-spectrum cepha antibiotic often grouped with the second-generation cephalosporins.

Fosfomycin Disodium Salt is an antibiotic produced by Streptomyces fradiae. It is used to treat uncomplicated urinary tract infections and is used for susceptibility studies of Klebsiella pneumoniae.

Amoxicillin Sodium is a moderate-spectrum, bacteriolytic, β-lactam antibiotic. It is effective against a variety of other gram-negative and gram-positive bacteria.

Prepared by acylation of chloramphenicol with succinic anhydride to provide a water soluble pro-drug; represents an alternative prodrug strategy for chloramphenicol that has found a niche in surface antibiotic treatment in surgery; acts as a prodrug, forming chloramphenicol in the presence of succinate dehydrogenase.

Azlocillin is an acylampicillin antibiotic with an extended spectrum of activity and greater in vitro potency than the carboxy penicillins. Azlocillin is similar to mezlocillin and piperacillin. It demonstrates antibacterial activity against a broad spectrum of bacteria, including Pseudomonas aeruginosa and, in contrast to most cephalosporins, exhibits activity against enterococci.

Tiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry. Tiamulin is active against gram-positive bacteria, mycoplasmas, and anaerobes, including Brachyspira hyodysenteriae.

Ceftezole is a semisynthetic first-generation cephalosporin with antibacterial activity. Ceftezole may decrease the excretion rate of Abacavir which could result in a higher serum level. Ceftezole Sodium is the sodium salt form of ceftezole.

Pefloxacin is a synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria. Pefloxacin inhibits the activity of microbial DNA gyrase and topoisomerase IV. This disrupts DNA replication and prevents cell division.

TAN-420C is an antibiotic produced by Streptomyces hygroscopicus. TAN 420C is known to exhibit antitumour activity.

Antibiotic TAN 420E is a hydroquinone analogue of herbimycin A with antibacterial, antifungal and antiprotozoan activity.

TPU-0037A is a neurogenesis agent isolated from Streptomyces.

Flumequine is a synthetic chemotherapeutic antibiotic, inhibiting topoisomerase II with IC50 of 15 μM. It is a first-generation fluoroquinolone antibacterial that has been removed from clinical use and is no longer marketed.

Sulfapyridine sodium is the first-generation sulfa antibiotic, one of the first compounds used to treat pneumonia. It has anti-inflammatory effects and can be used for immunodeficiency research.

Pipemidic acid is a synthetic quinolone antibiotic agent as an ATP-sensitive K+ channel blocker.

Micronomicin is a trisaccharide pentaaminoglycoside antibiotic belonging to the gentamicin class. It is isolated from micromonospora sagamiensis var. It has broad activity against Gram-positive and Gram-negative bacteria and induces neuromuscular obstruction.