Antibiotics

It is produced by the strain of Trichoderma harzianum OUPS-N115. Harzialacton B has weak cytotoxicity to P388 leukemia cells with ED50 of 60 μg/mL.

It is an antibiotic produced by the strain of Oudemansiella mucida Xerula melanctricha. It acts on fungi to inhibit the synthesis of protein, RNA and DNA.

It is an antibiotic produced by the strain of Oudemansiella mucida Xerula melanctricha. It acts on fungi to inhibit the synthesis of protein, RNA and DNA.

It is produced by the strain of Streptomyces lavendulae SANK-64297. It is a nematocidal substance.

Kanglemycin A (KglA) is related to rifampicin, an antibiotic that functions by binding to bacterial RNA polymerase. KglA binds bacterial RNA polymerase at the rifampicin-binding pocket but maintains potency against RNA polymerases containing rifampicin-resistant mutations. KglA has antibiotic activity against rifampicin-resistant Gram-positive bacteria and multidrug-resistant Mycobacterium tuberculosis.

It is a lactone antibiotic produced by the strain of Streptomyces sp. A 415-Z3. It has anti-gram-positive activity. 100 μg/mL can inhibit HeLa cells, and it has inhibitory effect on Ehrlich ascites carcinoma and solid carcinoma.

Tunicamycin, a mixture of homologous nucleoside antibiotics, has been used to study the effect of N-linked glycosylation of human proton-coupled folate transporter (HsPCFT) in HeLa cells. Tunicamycin blocks the formation of N-glycosidic linkages by inhibiting the first step in glycoprotein synthesis. It exhibits a range of biological activities, including antimicrobial, antivirus, and antitumor effects. It is produced by certain bacteria, including Streptomyces lysosuperficus and Streptomyces chartreusis.

Sulbenicillin is a penicillin antibiotic.

Erythromycin lactobionate is a soluble salt of erythromycin that is a macrolide antibiotic which inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. Erythromycin is effective against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus.

Cefuroxime is a cephalosporin antibiotic. It is used to treat many kinds of bacterial infections, including severe or life-threatening forms. Cefuroxime axetil is a prodrug of the cephalosporin cefuroxime, which is a second generation oral cephalosporin antibiotic with in vitro antibacterial activity against several gram-positive and gram-negative organisms.

Temocillin is a β-lactamase-resistant penicillin that effects against gram-negative bacteria.

Tosufloxacin is a fluoroquinolone antibiotic with activity against Gram-positive and Gram-negative aerobic bacteria, anaerobic bacteria and Chlamydia trachomatis. It acts as an inhibitor of bacterial DNA gyrase and topoisomerase IV.

Nisin A is a polycyclic antibacterial peptide produced by the bacterium Lactococcus lactis that is used as a food preservative.

Ethionamide is an antibiotic used in the treatment of tuberculosis. Ethionamide is a part of a group of drugs used in the treatment of drug resistant TB called thioamides.

Magainin I is a peptide antibiotic with antibacterial and antiparasitic activities, originally extracted from the skin of Xenopus laevis. It has a broad spectrum of non-specific activity against a variety of microorganisms, including viruses, gram-positive and gram-negative bacteria, protozoa, yeast and fungi, and may also have hemolytic and cytotoxicity to cancer cells. Magainin 1 is a fungicide. Magainin 1 has an inhibitory effect on herpes simplex virus type 1 (HSV-1) and HSV-2.

Minocycline is a broad-spectrum tetracycline antibiotic, which has a broader spectrum than the other members of the group. It is effective against tetracycline-resistant staphylococcus infections. It is a bacteriostatic antibiotic and is classified as a long-acting type. It is the most lipid-soluble of the tetracycline-class antibiotics, giving it the greatest penetration into the prostate and brain. It is not a naturally-occurring antibiotic, but was synthesized semi-synthetically from natural tetracycline antibiotics by Lederle Laboratories in 1966. It is mainly used for the treatment of acne and other skin infections. Its application is very limited because of its side effects.

Valnemulin is a pleuromutilin antibiotic used to treat swine dysentery, ileitis, colitis and pneumonia.

Virginiamycin complex contains two streptogramin antibiotics, virginiamycin M1 (75%) and virginiamycin S1 (25%). It is an antibiotic used primarily in the treatment of staphylococcal infections, and to a less extent streptococcal infections.

Bambermycin (flavomycin) is a complex of antibiotics obtained from Streptomyces bambergiensis and Streptomyces ghanaensis used as a food additive for beef cattle, dairy cattle, poultry and swine. The complex consists mainly of moenomycins A and C.

Enrofloxacin hydrochloride is a fluoroquinolone antibiotic commonly used in veterinary medicine.