Antibiotics

MS-282b is produced by the strain of Streptomyces tauricus. It inhibits calmodulin-dependent MLCK with an IC50 of 5.2 μmol/L. It has anti-gram-positive bacteria activity.

It is originally isolated from Actinomyces sp. MSD-92 has anti-gram-positive and anti-gram-negative activity, and the MIC of it against Escherichia coli was 2 μg/mL.

MSD-819 is extracted from Streptomycess ambofaciens. It has anti-gram-positive and anti-gram-negative bacteria activity.

Antibiotic N-1 is extracted from Streptomyces thermotolerans. It has the activity against gram-positive bacteria and mycoplasma.

It is a cyclopeptide produced by the strain of Bacillus sp. No 4691. N-4909 can stimulate the secretion of Apolipoprotein E in human hepatoma HEP G2 cells.

It is originally isolated from Streptomyces sp. NA22598. NA 22598A1 can inhibit independently attached DLD-1 cells with an IC50 of 0.3 μg/mL.

N-Acetylalanylanthranilamide is extracted from Penicillum sp. NI15501. It has anti-microbial activity against certain microorganisms, such as Methicillin-resistant Staphylococcus aureus (MRSA), Klebsiella pneumoniae, bacillus proteus vulgaris, Pseudomonas aeruginosa and so on.

NK 1001 is produced by the strain of Streptomyces kanamyceticus var.. NK 1001 has weak activity against gram-positive, gram-negative and mycobacterium bacteria.

FK 156 is an amphoteric peptide antibiotic originally isolated from Streptomyces olivaceogriseus C-353. It has immunological promoting effect.

It is a β-lactam antibiotic originally isolated from Nocardia uniformis subsp. tsuyamanensis. It has similar antibacterial activity to FR-29038.

Fosmidomycin is produced by the strain of Streptomyces lavendulae 8006. Fosmidomycin has anti-gram-positive and anti-gram-negative activities.

FR-198248, a new type of hydroxyl benzaldehyde compound, was isolated from the cultured broth of a fungal strain identified as Aspergillus terreus from morphological characteristics. FR-198248 exhibited anti-influenza virus activity in Madin-Darby canine kidney (MDCK) cells in vitro.

FR-900098 is produced by the strain of Streptomyces rubellomurinus subsp. indigoferus 24. FR-900098 has anti-gram-positive and anti-gram-negative activities.

FR-900490 is a new type of immunoactive substance isolated from Disocia sp. F-11809. It is effective in reversing the damage to bone marrow caused by mitomycin C.

This active molecular is an immunoactive substance produced by Paecilomyces carneus F-4882, an imperfect fungus. FR-901235 can lead the mitogen-induced lymphocyte proliferation to go back to a normal level after being suppressed by addition of immunosuppressive factor.

BE 14106 is produced by the strain of Streptomyces sp. It has weak anti-Pseudomonas aeruginosa activity and inhibition of mixed lymphocyte reaction (MLR) activity.

Antibiotic JI 20A is an aminoglycoside antibiotic originally isolated from Micromonospora purpurea.

L-156602 is extracted from Streptomyces sp. MA6348, and it is the antagonist of Anaphylatoxin C5a. It is also a cyclic depsipeptide antibiotic that is active against Gram-positive bacteria.

A glycolipid-type antibiotic related to the efrotomycin class; isolated from a streptomyces sp.; shows broad spectrum antibiotic activity against gram positive and gram negative bacteria

Nemadectin, the dominant member of a class of milbemycins, shows pronounced nematocidal and insecticidal activity.