Antibiotics

It is an antifungal steriod produced by the strain of Aspergillus ustus NF-8054. Mer-NF8054A has the activity against several Aspergillus fumigatus strains.

It is an antifungal steriod produced by the strain of Aspergillus ustus NF-8054. Mer-NF8054X has the activity against several Aspergillus fumigatus strains.

Mer WF3010 is an antifungal antibiotic of the Papulacandin group extracted from Phialophora cyclaminis Mer-WF 2010. It has the activity of anti-candida fungi, but has weak effect on other fungi.

It is originally isolated from Streptomyces sp. MF-EA-705. And the MIC of MF-EA-705alpha against Candida albicans was 1 g/mL.

MF-EA-705beta is an antifungal antibiotic isolated from Streptomyces sp. MF-EA-705.

MH-031 is produced by the strain of Streptomyces rishiriensis A-5969 with protective effects on the liver.

MJ347-81F4-B is originally isolated from Amycolatopsis sp. MJ347-81F4. It has good anti-gram-positive bacteria activity, including clinically isolated methicillin-resistant Staphylococcus aureus (MIC 0.05-0.2 μg/mL).

MK800-62F1 is produced by the strain of Streptomyces diastochromogenes MK 800-62F1. It is used to inhibit H2O2-induced apoptosis in MS-1 cells (NCI-H) and Jurkat cells (TCL-H), and camptothecin-induced apoptosis in Jurkat cells.

Leptocillin is extracted from Leptoaphaeria sp. L-179. It is resistant to several Gram-positive bacteria (Staphylococcus aureus 209P, Bacillus subtilis No. 119) and several Gram-negative bacteria (Klebsiella pneumoniae 22 # 3038, proteus singular GN310).

MK-7924, isolated from Coronophora gregaria, is an antibiotic with nematocidal effect. And the reproductive growth tests showed that the effective concentration against Caenorhabditis elegane was 100 μg/mL.

It is produced by the strain of Streptomyces sp. NCIB 11813. MM 14201 has a broad spectrum of antibacterial activity, especially against the bacteria of Serratia and Pseudomonas.

MM-17880 is originally isolated from Streptomyces olivaceus. It has anti-gram-positive and anti-gram-negative bacteria activities. Combined with amoxycillin, it has a synergistic antibacterial effect on Staphylococcus aureus and Klebsiella pneumoniae.

MM 42842 is originally isolated from Pseudomonas cocovenenans and has weak activity against gram-positive bacteria.

MM 46115 is produced by the strain of Actinomadura pelletieri. It has anti-parainfluenza virus 1 and 2 and anti-gram-positive bacteria activities.

It is a kind of glycopeptide antibiotic originally isolated from Amycolatatopsis orientalis NCIB 12608 with good activity against Gram-positive bacteria.

It is a kind of glycopeptide antibiotic originally isolated from Amycolatatopsis orientalis NCIB 12608 with good activity against Gram-positive bacteria.

It is a kind of glycopeptide antibiotic originally isolated from Amycolatopsis NCIB 40089 with good activity against Gram-positive bacteria.

It is a kind of glycopeptide antibiotic originally isolated from Amycolatopsis NCIB 40089 with good activity against Gram-positive bacteria.

MR304A is extracted from Trichoderma harzianum. It can inhibit the formation of melanin by Mushroom tyrosinase, Streptomyces bikiniensis and B16 melanoma cells, with IC50 (μg/L) of 7.5, 2.5 and 1.0, respectively.

MS-282a is produced by the strain of Streptomyces tauricus. It inhibits calmodulin-dependent MLCK with an IC50 of 3.8 μmol/L. It has anti-gram-positive bacteria activity.