Antibiotics

LL-F 28249lambda is a macrolide antibiotic with parasitic action from Streptomyces Cyaneogriseus sp. Noncyanogenus.

LL-Z 1220 is a natural antibiotic which contains a cyclohexene diepoxide ring system.

It is an anthracycline antibiotic derived from Nocardia brasiliensis IFM-0075.

M-230B is originally isolated from Myxococcus xanthus M516E. It has anti-gram-negative and weak anti-gram-positive activity.

It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 A1 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics.

It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 G1 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. And it also has a certain anti-Gram-negative bacteria activity.

It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 G2 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics.

Tetronasin is extracted from Streptomyces longisporoflavus. It has anti-gram-positive bacteria and anti-eimeria tenella activity.

MA144 G2 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects.

MA144 M1 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects.

MA144 M2 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects.

MA144 U1 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects.

MA144 S1 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects.

MC-031, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 10.6×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells.

MC-032, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 10.5×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells.

MC-033, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 1.06×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells.

MC-034, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 18.3×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells.

It is originally isolated from Streptomyces pactum. Mer-A2026A has the function of vasodilator and hypotension.

It is originally isolated from Streptomyces pactum. Mer-A2026B has the function of vasodilator and hypotension.

It is originally isolated from Metarrhizium sp. f3. And it is cytotoxic to some human tumor cells, such as K562, HT29, MCF7 and HT1080 cells.