Antibiotics

BE-19412B is an antitumor antibiotic extracted from the culture medium of Streptomyces sp. A19412. It is toxic to mouse and human tumor cells such as P388, Ehrlich, DLD-1, PC-13, MKN-45 and Colon 26, with IC50 of 0.9-5.4 μg/mL, and can prolong the survival time of CDF1 mice with Ehrlich cancer.

BE-29602 is a papulacandin antibiotic produced by Fusarium sp. F296O2. It has activity against Candida, Saccharomyces cerevisiae and other fungi, with an MIC of 0.20-0.7 μg/mL. It is cytotoxic and has an IC50 of 21 μg/mL to P388 murine leukemia cells.

BE-31405 is an antifungal antibiotic produced by Penicillum minioluteum F31405. It has activity against pathogenic fungi such as Candida albicans and Cryptococcus neoformans (MIC 3.13-6.25 μg/mL), and has no cytotoxicity to mammalian cells (such as P388 murine leukemia, etc.).

BE-32030A is an antitumor antibiotic produced by Nocardia sp. A32030. It has inhibitory effect on the growth of P388, DLD-h PC-13 and MKN-45 tumor cells.

BE-32030B is an antitumor antibiotic produced by Nocardia sp. A32030. It has inhibitory effect on the growth of P388, DLD-h PC-13 and MKN-45 tumor cells.

BE-32030C is an antitumor antibiotic produced by Nocardia sp. A32030. It has inhibitory effect on the growth of P388, DLD-h PC-13 and MKN-45 tumor cells.

BE-32030D is an antitumor antibiotic produced by Nocardia sp. A32030. It has inhibitory effect on the growth of P388, DLD-h PC-13 and MKN-45 tumor cells.

BE-32030E is an antitumor antibiotic produced by Nocardia sp. A32030. It has inhibitory effect on the growth of P388, DLD-h PC-13 and MKN-45 tumor cells.

BE-40665D is an antibiotic produced by Actinoplanes sp. A4O665. It has moderate anti-gram-positive bacteria activity and has no effect on gram-positive bacteria.

BL-5808 is a polyether antibiotic produced by Streptomyces hygroscopicus mutant strain FERM-P 4102 (NRRL 8180). It has anti-coccidial activity.

BL-S784 is a semi-synthetic cephalosporin made from 7-aminocephalosporin (7-ACA). It has anti-gram-negative bacteria and gram-positive cocci activity.

BMG59-R2 is a peptide antibiotic produced by Bacillus megaterium BNG59-R2. It can inhibit the activity of alkaline phosphatase and also has anti-tumor activity.

BMS-181184 is an antifungal antibiotic produced by Actinomadura sp. AB1236 in a medium containing D-serine or D-cycloserine. It has activity against pathogenic fungi such as yeast, Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus and Trichophyton.

BMS-181532 is an antifungal antibiotic produced by Actinomadura sp. AB1236 in a medium containing D-serine or D-cycloserine. It has activity against pathogenic fungi such as yeast, Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus and Trichophyton.

BMY-28160 is an ester peptide antibiotic produced by Bacillus circulans H913-B4. It has anti-gram-positive bacteria, negative bacteria, anaerobic bacteria and fungi activity.

BMY-28190 is an antiviral antibiotic produced by Streptoalloteichus hindustanus E46594, which is a complex composed of D-a.Z-diaminobutyric acid. It has weak anti-gram-positive and negative bacteria activity, but has a strong inhibitory effect on type 1 herpes simplex virus (HSV-1), with IC50 of 2.8 μg/mL.

BMY-28438 is an antitumor antibiotic produced by Streptomyces tropolofaciens No. K611-97. It has a strong inhibitory effect on B-16 melanoma cells, with an IC50 of 0.04 μg/mL. It has weak anti-bacterial and fungal activity.

Cepabactin is an antibiotic produced by Pseudomonas sp. BN-227. It has anti-gram-positive and negative bacteria activity.

BN-227F is an antibiotic produced by Pseudomonas sp. BN-227. It has anti-gram-positive and negative bacteria activity.

Bu-1709E1 is an aminoglycoside antibiotic produced by Bacillus circulans YQW-B-6. It has anti-gram-positive bacteria, negative bacteria and mycobacterial activity.