Antibiotics

CP 91244 is a polyether antibiotic originally isolated from Actinomadura roseorufa. It has anti-gram-positive bacteria, spirochete, treponema activity, and it also has the effect on chicken coccidiosis.

It is produced by the strain of Actinomadura roseorufa 263606. CP-120509 has anti-gram-positive bacteria, spirochete and spirochete activity, and also has a good anti-coccidiosis effect caused by Eimeria acervulina, E. tenella.

It is originally isolated from Hericium ramosum CL 24240. CP 412065 selectively inhibited κ-opioid receptor binding with IC50 > 200 μnmol/L.

CYL-2 is a cyclic tetrapeptide produced by the strain of Cylindrocladium scoparium. It has anti-bacterial activity.

D788-1 is produced by the strain of Streptomyces sp. D788. It had inhibitory activity against L1210 with IC50 of 0.027 μg/mL.

DB-2073 is produced by the strain of Pseudomonas B-9004. It has the activity against streptococcus pneumoniae and tinea gypsum mold.

Quinocarcin is originally isolated from Streptomyces melanovinaceus. It has anti-gram-positive bacteria and Klebsiella pneumoniae activity, and also has anti-mouse leukemia P388 effect.

DC 81 is originally isolated from Streptomyces roseiscleroticus DO-81. It has weak anti-gram-positive, anti-gram-negative and tumor activity.

It is originally isolated from Streptomyces lugeogriseus 86. DC 86M has anti-Gram-positive bacteria and weak anti-Gram-negative bacteria activity, and can inhibit mouse sarcoma 180 cells.

It is originally isolated from Actinomadura sp. DC92-B is mainly resistant to Gram-positive bacteria, and it also has anti-tumor activity.

It is originally isolated from Actinomadura sp. and DC92-D is mainly resistant to Gram-positive bacteria.

DC-102 is produced by the strain of Streptomyces sp. It has anti-gram-positive bacteria activity and anti-tumor effect.

DOB-41 is produced by the strain of Pseudomonas DOB-41. It has strong anti-gram-positive bacteria activity, and has the effect of inhibiting tumor. It prolongs the survival of transplanted leukemia P388 mice.

EI-2128-1 is originally isolated from Penicillum sp. E-2128. It selectively inhibited ICE, and the IC50 of recombinant human ICE was 0.59 μmol/L. It also has anti-Gram-positive bacteria such as Bacillus subtilis, Staphylococcus aureus and Enterococcus enterococcus.

EM2487 is produced by the strain of Streptomyces sp. Mer-2487. It inhibited HLV-1 replication in both chronically and acutely infected cells. The action occurs during the post-integration phase of the HIV-1 provirus DNA in the HIV-1 replication cycle.

ES 242-1 is produced by the strain of Verticillium sp. SPC-15898. It inhibited the [3H] thienyl cyclohexypiperidine ([3H] TCP) binding membrane of rat cell process by IC50 of 116 nmol/L.

ES 242-2 is produced by the strain of Verticillium sp. SPC-15898. It inhibited the [3H] thienyl cyclohexypiperidine ([3H] TCP) binding membrane of rat cell process by IC50 of 2.9 μmol/L.

ES 242-3 is produced by the strain of Verticillium sp. SPC-15898. It inhibited the [3H] thienyl cyclohexypiperidine ([3H] TCP) binding membrane of rat cell process by IC50 of 2.9 μmol/L.

ES 242-4 is produced by the strain of Verticillium sp. SPC-15898. It inhibited the [3H] thienyl cyclohexypiperidine ([3H] TCP) binding membrane of rat cell process by IC50 of 25μmol/L.

ES 242-5 is produced by the strain of Verticillium sp. SPC-15898. It inhibited the [3H] thienyl cyclohexypiperidine ([3H] TCP) binding membrane of rat cell process by IC50 of 1.0μmol/L.