Antibiotics

CJ-13136 is originally isolated from Pseudonocardia sp. CL38489. It has highly selective anti-helicobacter pylori activity.

CJ 14258, produced by the strain of Hericium ramosum CL 24240, is a selective binding inhibitor of κ-opioid receptor with IC50 of 32 μmol/L.

It is originally isolated from Marasmiellus sp. CL21624. CJ-14877 inhibited human blood interleukin-1β (IL-1β) production induced by lipoglycan (LPS) with an IC50 of 0.1 μmol/L.

It is originally isolated from Marasmiellus sp. CL21624. CJ-14897 inhibited human blood interleukin-1β (IL-1β) production induced by lipoglycan (LPS) with an IC50 of 0.059 μmol/L.

CJ-15183 is originally isolated from Aspergillus aculeatus CL38916. It has strong inhibitory activity against rat liver, human liver and Candida albicans SSase, and has antifungal activity against filamentous fungi and yeast-like fungi.

CJ-15208 is produced by the strain of Ctenomyces serratus. It selectively inhibits κ-opioid receptor binding with an IC50 of 47 nmol/L.

CJ 15544 is a potent κ-opioid receptor antagonist from a fungus, Hericium ramosum CL 24240.

CJ-15696 is a furopyridine antibiotic produced by the strain of Cladobotryum varium CL12284. It has moderate activity against gram-positive bacteria, including drug-resistant bacteria.

CJ-16169 is a furopyridine antibiotic produced by the strain of Cladobotryum varium CL12284. It has weak activity against gram-positive bacteria.

CJ-16170 is a furopyridine antibiotic produced by the strain of Cladobotryum varium CL12284. It has weak activity against gram-positive bacteria.

CJ-16173 is a furopyridine antibiotic produced by the strain of Cladobotryum varium CL12284. It has weak activity against gram-positive bacteria.

It is originally isolated from Seimatosporium sp. CL28611. CJ-15801 has only anti-MRSA activity with MIC of 6.25-50 μg/mL.

It is originally isolated from CL39457. CJ-16367 is mainly resistant to Gram-positive bacteria, including multi-drug resistant strains, but its activity is weak.

It is produced by the strain of Pezicula sp. CJ-11877. CJ-17572 has anti-MRSA and Enterococcus faecalis activity with MIC of 10-20 μg/mL.

CJ-17665 is produced by the strain of Aspergillus ochraceus. It inhibits growth of multi-drug resistant MRSA, Streptococcus pyogenes and Enterococcus faecalis with MIC of 12.5, 12.5 and 25 μg/mL, respectively.

CJ-19784 is an antibiotic which is mainly resistant to Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus. It is produced by the strain of Acanthostigmella sp. CL-12082.

CJ-21058 is a SecA inhibitor originally isolated from CL47745. It shows antiprotozoal effects (IC50 = 7 μM, T. brucei) and inhibits post-translational protein transport into the endoplasmic reticulum. It shows antibacterial and antifungal effects in vivo.

CP-35587 is resistant to gram-positive cocci, but it has no effect on penicillin-resistant Staphylococcus aureus and is active against gram-negative bacteria.

CP-82009 is a polyether antibiotic originally isolated from Actinomadura sp.. It shows strong resistance to chicken coccidiosis, and also has anti-gram-positive bacteria and spirochetes activity.

CP 91243 is a polyether antibiotic originally isolated from Actinomadura roseorufa. It has anti-gram-positive bacteria, spirochete, treponema activity, and it also has the effect on chicken coccidiosis.