Antibiotics

It is produced by the strain of Flagelloscypha pilatii JK 322. Like Marasmic acid, it has inhibitory effects on bacteria and fungi, and has strong inhibitory effects on the incorporation of thymidin and ureidin into DNA and RNA in Ehrlich carcinoma ascites cells. It can cause frameshift mutations in Salmonella typhimuium TA98.

It is produced by the strain of Penicillium sp., Pen. amarum. It is a nitrogen-containing heterocyclic antibiotic. It has anti-yeast activity.

It is produced by the strain of Penicillium vulpinum F-4148. In in vitro test, it can inhibit P388, L 1210, HL-60, KB and other tumor cell lines with IC50 (μg/mL) of 0.8, 0.8, 0.8, 0.25, respectively. It has only very weak antibacterial activity against the microorganisms tested.

It is produced by the strain of Streptoverticillium olivoreticuli subsp. neoenacticus. It has anti-fungal, yeast, some mycobacterium effects, but no anti-bacterial effect.

It is produced by the strain of Piptoporus sp. Lu 9-1. It has broad antibacterial spectrum, it inhibits Staphylococcus aureus, enterococcus faecalis, Bacillus subtilis, Escherichia coli, Candida albicans with MIC (μg/mL) of 0.78-6.25, 1.56, 1.00, 12.5, 6.25, respectively.

Sch 40832 is an antibiotic produced by Micromonospora carbonacea var africana. It exhibits activity against gram-positive bacteria with MIC of 0.1-1.0 μg/mL.

Sch 42137 is an antifungal antibiotic isolated from Actinoplanes sp. It exhibited MIC values less than 0.125 μg/mL against yeasts and dermatophytes.

Sch 47554 is an antifungal antibiotic produced from Streptomyces sp. SCC-2135.

Sch 47555 is an antifungal antibiotic produced from Streptomyces sp. SCC-2135.

Sch 57404 is an antifungal antibiotic produced by an unidentified fungus SCF1082A.

Pseudopyronines B is an alpha-pyrone antibiotic produced by Pseudomonas fluorescens. It exhibits activity against Staphylococcus aureus and Escherichia coli with IC50 of 2.5 and >64 μg/mL, respectively.

Sch 484129 is a glycolipid antibiotic isolated from the fermentation broth of Basidiomycete HAM-240. It displayed antifungal activity against Saccharomyces and Aspergillus strains.

Sch 484130 is a glycolipid antibiotic isolated from the fermentation broth of Basidiomycete HAM-240. It displayed antifungal activity against Saccharomyces and Aspergillus strains.

Sch 528647 is an antitumor antibiotic produced by Aspergillus fumigatus.

Sch 575867 is an antifungal antibiotic isolated from a deep-water marine sponge Astroscleridae. It is effective against brewer's yeast with MIC of 15 μg/mL.

SF-773α is an antibiotic produced by Streptomyces sp. It is active against gram-positive bacteria.

SF-1623 is a cephamycin antibiotic produced by the the fermentation of Streptomyces chartreusis. It is active against gram-negative bacteria.

SF 2315 A is a quinone antibiotic produced by Excellospora viridilutea SF2315. It exhibits inhibitory effect against Avian myelobastosis virus reverse transcriptase with IC50 of 100 μg/mL. It has weak activity against gram-positive bacteria.

SF 2315 B is a quinone antibiotic produced by Excellospora viridilutea SF2315. It exhibits inhibitory effect against Avian myelobastosis virus reverse transcriptase with IC50 of 40 μg/mL. It has weak activity against gram-positive bacteria.

SF-2330 is a quinone antibiotic produced by Streptomyces sp. SF-2330. It exhibits activity against gram-positive bacteria.