Antibiotics

γ-Rubromycin is a quinone antibiotic originally isolated from Streptomyces. It is effective against Gram-positive bacteria.

Saccharocin is produced by the strain of Saccharopolyspora sp. AC-3440. It is effective against gram-positive and negative bacteria, and also against aminoglycoside antibiotic-resistant bacteria.

Safracin A is produced by the strain of Pseudomonas fluorescens A22 (IFO 14128). It has anti-gram-positive bacteria, gram-negative bacteria and anti-tumor effect.

Safracin B is a new antibiotic from the family of Safracin produced by Pseudomonas fluorescens A2-2. Safracin B exhibits broad spectrum antimicrobial and strong antitumor activities.

It is produced by the strain of Str. albospoeus var. labilomyceticus A955-y3. It's a sugar antibiotic. It has anti-gram-positive bacteria, mycobacterium activity. It had cytotoxic effect on HeLa cells and Yoshida sarcoma cells. Each rat (Transplantation of airy ascites carcinoma in mice) is given Labilomycin of 250 μg/d, it can inhibit tumor and prolong life. It has a protective effect on mice infected with S. aureus. Serum does not affect its antibacterial activity.

It is produced by the strain of Lachnum papyraceum. It has weaker activity against bacteria, yeast and filamentous fungi. It has cytotoxic activity against L1210, HeLa, KB and other cell lines.

It is produced by the strain of Lachnum papyraceum. It has weaker activity against bacteria, yeast and filamentous fungi. It has cytotoxic activity against L1210, HeLa, KB and other cell lines.

It is produced by the strain of Lactarius deliciosus. It is an aromatic derivative antibiotic. It can inhibit the growth of Mycobacterium tuberculosis, but the effect is not strong.

It is produced by the strain of Streptomyces sp. AK 623. It's an antitumor antibiotic. It has weak anti-gram-positive bacterial activity. It can inhibit human tumor cells HMO2, MCF7 and Hep G2 with GI50 (μg/mL) of 1.9, 0.85 and 5.11, respectively.

It is produced by the strain of Str. tanashiensis IM 8442T. It's a quinone antibiotic. It has the activity of anti-gram-positive bacteria and some gram-negative bacteria, but the effect of anti-gram-negative bacteria is weak and has no effect on fungi. Lactoquinomycin A has stronger antibacterial activity than Lactoquinomycin B. It inhibits a variety of cell lines including lymphoma L5178Y progenitor, adriamycin resistant, bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID50 (μg/mL) of 0.43, 0.21, 0.19, 0.16, 0.2 and 0.12, respectively.

It is produced by the strain of Str. sp. AA0310. It can inhibit 5-fat oxygenase with IC50 of 6.08 μmol/L, but dose not inhibit lipid peroxidation. It has the activity of anti-gram-positive bacteria, not anti-gram-negative bacteria.

It is produced by the strain of Lambertella hicoriae, Lam. cornimaris. It's a quinone antibiotic. It has anti-gram-positive bacterial and fungal activity.

It is produced by the strain of Str. violaceoniger NRRL 2834. It's a macrolide antibiotic. It has weak anti-gram-positive bacterial activity. It has cross-resistance with Picromycin and synergistic effect with Lankacidin.

It is produced by the strain of Str. lasaliensis. It has anti-gram-positive bacteria and protozoa activity. It is added to feed to prevent coccidiosis in chickens.

It is produced by the strain of Str. lasaliensis. It has anti-gram-positive bacteria and protozoa activity. It is added to feed to prevent coccidiosis in chickens.

It is produced by the strain of Str. lasaliensis. It has anti-gram-positive bacteria and protozoa activity. It is added to feed to prevent coccidiosis in chickens.

It is produced by the strain of Str. lavendulae C-22030. It's a quinone antibiotic. It has anti-bacterial and fungal effect, but the anti-bacterial effect is weaker than Streptonigrin, while the anti-fungal effect is stronger than Streptonigrin.

It is produced by the strain of Str. lavendulae subsp. brasillicus. It has strong activity against Staphylococcus aureus, Staphylococcus epidermococcus and Streptococcus faecalis with ED50 (mg/kg) of 2.33, 1.68 and 13.2, respectively (In vivo test in mice, abdominal infection, subcutaneous administration). It has no anti-gram-negative bacteria and fungi activity.

It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells.

It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells.