Antibiotics

Negamycin is a peptide antibiotic that has broad-spectrum antibacterial activity.

Neihumicin is produced by the strain of Micromonospora neihuensis Wu, sp. nov. Neihumicin is resistant to beer saccharomyces yeast and Penicillium italium Wehmer, but not to bacteria.

It is produced by the strain of Poria corticola B-841, 71280. Nemotin has the activity against gram-positive bacteria, mycobacterium and fungus, and also against gram-negative bacteria, but the activity is weak.

It is produced by the strain of Poria corticola B-841, 71280. Nemotinic acid has the activity against gram-positive bacteria, mycobacterium and fungus, and also against gram-negative bacteria, but the activity is weak. And its activity is stronger than Nemotin.

Neocopiamycin A is produced by the strain of Str. hygroscopicus var. crystallogenes. It is broad-spectrum resistant to gram-positive bacteria, yeast and filamentous fungi.

Neocopiamycin B is produced by the strain of Str. hygroscopicus var. crystallogenes. Its antifungal activity is stronger than that of copiamycin and Neocopiamycin A.

Neoenactin A is originally isolated from Streptoverticillium olivoreticuli subsp. neoenacticus. It has strong anti-yeastlike and filamentous fungal effects.

Neoenactin B1 is originally isolated from Streptoverticillium olivoreticuli subsp. neoenacticus. It has strong anti-yeastlike and filamentous fungal effects.

Neoenactin B2 is originally isolated from Streptoverticillium olivoreticuli subsp. neoenacticus. It has strong anti-yeastlike and filamentous fungal effects.

Neomycin B is originally isolated from Str. fradiae 3535. It is mainly resistant to bacteria and mycobacteria, and its activity is the strongest of the three components.

Neomycin C is originally isolated from Str. fradiae 3535. It is mainly resistant to bacteria and mycobacteria.

Neosordarin is originally isolated from Sordaria araneosa Cain. Neosordarin has antifungal activity and inhibits S. Cerevisia with the IC50 of 0.2-0.3 μg/mL.

Neotelomycin is originally isolated from Str. sp. 128 and it is resistant to gram-positive bacteria.

It is produced by the strain of Str. griseoviridus P8648. Neoviridogrisein I has been used to resist gram-positive bacteria and mycoplasma.

It is produced by the strain of Str. griseoviridus P8648. Neoviridogrisein II has been used to resist gram-positive bacteria and mycoplasma.

It is a new macrolide antibiotic produced by the strain of Str. rimosus NRRL 3016. Niddamycin is resistant to gram-positive bacteria.

Nidulin is produced by the strain of Asp. nidulans NRRL 2006. It is resistant to mycobacterium but not very effective.

Nikkomycin Lx is originally isolated from Streptomyces tendae TU901. Although it is a microcomponent, it is relatively stable and has stronger anti-candida albicans activity than other components.

Nikkomycin Lz is originally isolated from Streptomyces tendae TU901. Although it is a microcomponent, it is relatively stable and has stronger anti-candida albicans activity than other components.

Nisamycin is originally isolated from Str. sp. K106. It has stronger anti-gram-positive bacteria and weaker anti-fungal and individual gram-negative bacteria activities. And it has weak cytotoxic effect. The IC50 of mouse leukemia P388 cells was 4.8 μg/mL.