Antibiotics

It is a directed biosynthetic analogue of chlorothricin. It is produced by a chlorothricin-producing strain of streptomyces antibioticus using media supplemented with potassium bromide. It exhibits similar properties to chlorothricin.

It is produced by the strain of Actinomycete strain MST-8651. It belongs to a novel class of antibiotics, possessing a new terpenylated diketopiperazine structure, with antibacterial, antifungal and anthelmintic activity.

It is produced by the strain of Actinomycete strain MST-8651. It belongs to a novel class of antibiotics, possessing a new terpenylated diketopiperazine structure, with antibacterial, antifungal and anthelmintic activity.

It is produced by the strain of Actinomycete strain MST-8651. It belongs to a novel class of antibiotics, possessing a new terpenylated diketopiperazine structure, with antibacterial, antifungal and anthelmintic activity.

It is an amphoteric, 13-member, linear peptide featuring 3,5-dihydroxyphenylalanine and a terminal dicarboxylate amino acid. It is isolated from Streptomyces sp. DSM 11171. It is a potent antiviral agent with antibacterial activity, including MRSA. It specifically inhibits the enzymes mura and murc. It inhibits cell-to-cell transfer between HIV-infected T cells, uninfected CD4+ T cells, and the DC-SIGN-mediated viral transfer to CD4+ T cells.

It is a broad spectrum antifungal metabolite isolated from several fusarium species. It exhibits low zoo-toxicity as evidenced by a lack of toxicity against artemia salina. It is a useful candidate for control of postharvest crop diseases.

It is a macrolide antibiotic produced by the strain of Str. kitasatoensis. It has strong anti-gram-positive bacterial effect, and also has an effect on spirochetes, rickettsium and Chlamydia.

It is a complex family of macrocyclic lactones containing a highly characteristic spiroketal group. It is a highly selective and potent nematocide and insecticide produced by streptomyces hydroscopicus subsp. Aureolarcrimosus. It is a minor member of a group of analogues containing a 25-isopropyl substituent.

It is a macrocylic polyol lactone antibiotic isolated from several species of streptoverticillium. It has the activity against gram-positive bacteria and has weak activity against gram-negative bacteria. It is an important bioprobe for understanding membrane channels.

It is a mixture of the two most abundant milbemycin analogues, A3 and A4. It is the macrolide antibiotic produced by streptomyces hydroscopicus subsp. Aureolarcrimosus. It is a highly selective and potent insecticide and acaricide used as an agri-chemical for crop protection.

It is a thiopeptide antibiotic isolated from the culture broth of Bacillus pumilus as a main component of the micrococcin P complex.

It is a 10-membered macrocyclic lactone antibiotic produced by Nocardia sp. It exhibits potent activity against gram-positive bacteria. It has been shown to enhance retinoate-induced cell differentiation.

It is an antibiotic produced by the strain of Saccharopolyspora hirsuta and Nocardia argentinensis. It is a co-metabolite of nargenicin, bearing the core macrocyclic lactone but lacking the pyrrole ester. It has anti-gram-positive bacteria and anaerobic bacteria activity.

It is a polyether antibiotic produced by Str. aureo faciens NRRL 5758. It has broad spectrum activity against gram-positive bacteria, anaerobic bacteria and mycoplasma. It also has antiviral and limited antifungal activity.

It is a symmetric dimer antibiotic isolated from an uncharacterised species of penicillium. It displays significant antibacterial activity against a wide range of gram-positive bacteria.

It is the major component (>80%) of the commercial anthelmintic, ivermectin. It exerts its anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. It is also a potent insecticide.

It is the simplest of the macrocyclic thiazole peptide antibiotic first isolated from bacillus badius and bacillus cereus. It has anti-gram-positive bacteria activity.

It is a mixture of eight cationic cyclic decapeptides antibiotic produced by bacillus brevis. It has a broad spectrum of antimicrobial activity against gram-positive and Gram-negative bacteria. Tyrocidine A is the major component of the tyrothricin complex which is used for treatment of topical infection. It acts by disturbing lipid bilayers of the bacterial cell membrane.

It is an anticancer antibiotic first isolated from S. cyaneogriseus ssp. noncyanogenus (LL-F28249). It has more selective action against mammalian tumour cell lines than Oligomycin A, exhibiting only weak antifungal and nematocidal activity.

Streptochlorin is a metabolite originally isolated from Streptomyces sp. It exhibits antiangiogenesis, antiproliferation and antiallergic activities. It inhibits TNF-α-induced NF-κB activation.