Antifungal

Antifungal

Catalog Product Name / CAS / Description Structure
BBF-01858

Fungichromin (6834-98-6)

Inquiry

A pentaene antifungal produced by streptomyces; exhibits broad spectrum antifungal and antitumor activity and, like filipin, acts via interaction with cell membrane sterols.

BBF-02576

Pneumocandin B0 (135575-42-7)

Inquiry

Pneumocandin B0 is a lipopeptide antibiotic produced by Zalerion arboricola. It has a strong anti-Candida effect. It has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL.

BBF-02577

Pneumocandin C0 (144074-96-4)

Inquiry

Pneumocandin C0 is a lipopeptide antibiotic produced by Zalerion arboricola. It has a strong anti-Candida effect. It has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL. Pneumocandin C0 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi.

BBF-02614

Nystatin (1400-61-9)

Inquiry

Nystatin, which belongs to the polyene group of antimycotics, is frequently used as a topical agent in the treatment of oro-pharyngeal candidosis.

BBF-03027

Verlamelin (74758-64-8)

Inquiry

It is a depsipeptide antibiotic produced by the strain of Fungi MF 4683. It has anti-fungal activity against plant pathogens.

BBF-03422

Trichodermin (4682-50-2)

Inquiry

Trichodermin is a terpenoid antibiotic which has anti-fungal and protozoal effects. It is originally isolated from Trichoderma viride.

BBF-03844

Anidulafungin (166663-25-8)

Inquiry

Anidulafungin, is a semisynthetic echinocandin that inhibits glucan synthase, an enzyme important in the formation of (1→3)-β-D-glucan, a major fungal cell wall component, and thus is used as an antifungal drug.

BBF-04053

Micafungin sodium (208538-73-2)

Inquiry

Micafungin Sodium is an inhibitor of 1,3-beta-D-glucan synthesis, used as an antifungal drug.

BBF-04146

Aureobasidin A (127785-64-2)

Inquiry

Aureobasidin A is a cyclic depsipeptide antibiotic isolated from the filamentous fungus Aureobasidium pullulans R106. It is an antifungal agent that inhibits phosphorylceramide synthase.

BBF-05736

Polyoxorim (22976-86-9)

Inquiry

Polyoxorim is a member of the class of polyoxins that is isolated from the soil organism Streptomyces cacaoi var. asoensis. Polyoxorim exhibits fungicidal properties and may be used on rice, industrial grounds, golf courses and parks. It has a role as an EC 2.4.1.16 (chitin synthase) inhibitor and an antifungal agrochemical. It is a polyoxin and an antibiotic fungicide.

BBF-05831

Nikkomycin Z is a nucleotide peptide from Streptomyces tendae with antifungal effects. Nikkomycin Z is a selective and competitive inhibitor of chitin synthesis and acts as a competitive analog of the chitin synthetase substrate UDP-N-acetylglucosamine.

BBF-05832

O-Desulfo Micafungin is an impurity of caspofungin or micafungin. Micafungin is a polyene antifungal medication used to treat and prevent invasive fungal infections including candidemia, abscesses and esophageal candidiasis.

BBF-05833

FR 901379 (144371-88-0)

Inquiry

FR 901379 is an impurity of Micafungin, a lipopeptide compound that acts as an antifungal agent with activity against Aspergillus and Candida species. FR901379 is an echinocandin-like antifungal lipopeptide with inhibitory activity against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = <0.003-1.9 μg/ml). FR 901379 has a protective effect against C. albicans infection in mice (ED50 = 1.1 mg/kg). It also reduces the number of lung cysts and trophozoites in a mouse model of Plasmodium carinii infection.

BBF-05834

FR 179642 (168110-44-9)

Inquiry

FR 179642 is an impurity of Micafungin, which is an antifungal agent.

BBF-05835

1-​[(4R,​5R)​-​4,​5-​dihydroxy-​L-​ornithine]​-Echinocandin B is an intermediate of Anidulafungin, an echinocandin antifungal drug.

BBF-05840

Diniconazole (83657-24-3)

Inquiry

Diniconazol is a chemical compound belonging to chlorine group of conazole. It is used as a fungicide. It inhibited lanosterol 14 alpha-demethylation catalyzed by a yeast cytochrome P-450 strongly.

BBF-05890

Aminocandin (227472-48-2)

Inquiry

Aminocandin, a new representative of the echinocandins, has broad-spectrum in vitro activity against Aspergillus and Candida spp. It is used as an anti-infective agent and antifungal drug. It acts by targeting glucans in the fungal cell walls.

BBF-05891

Tetrahydroechinocandin B, a cyclic hexapeptide containing a fatty acyl side chain, inhibits 1,3-beta-D-glucan synthesis. It is an intermediate of anidulafungin.

BBF-05906

Triclosan (3380-34-5)

Inquiry

Triclosan is a broad-spectrum antibacterial and antifungal agent added in consumer products such as toothpaste, soaps, detergents, etc.

BBF-05908

Dichlorophen is an antimicrobial agent with activity against cestodes, protozoa, fungi, and bacteria.

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