Antiviral

Antiviral

Catalog Product Name / CAS / Description Structure
BBF-04047

Ganciclovir (82410-32-0)

Inquiry

Ganciclovir is an antiviral drug for feline herpesvirus type-1 with IC50 of 5.2 μM.

BBF-04651

Plitidepsin (137219-37-5)

Inquiry

Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin shows potent anticancer activity against a large variety of cultured human cancer cells, inducing apoptosis by triggering mitochondrial cytochrome c release, initiating the Fas/DC95, JNK pathway and activating caspase 3 activation. This agent also inhibits elongation factor 1-a, thereby interfering with protein synthesis, and induces G1 arrest and G2 blockade, thereby inhibiting tumor cell growth.

BBF-05725

Megalomicin (129428-69-9)

Inquiry

Megalomicins are a family of macrolide antibiotics produced by the soil bacterium Micromonospora megalomicea. They exhibit antiparasitic, antiviral and antibacterial activity, and are effective against both Gram-positive and Gram-negative bacteria.

BBF-05847

T 705 (259793-96-9)

Inquiry

Favipiravir, also known as T-705 or Avigan, is an experimental antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses. Like some other experimental antiviral drugs (T-1105 and T-1106), it is a pyrazinecarboxamide derivative. Favipiravir is active against influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as other flaviviruses, arenaviruses, bunyaviruses and alphaviruses. Activity against enteroviruses and Rift Valley fever virus has also been demonstrated.

BBF-05848

Foscarnet Sodium inhibits viral RNA polymerases, reverse transcriptases and DNA polymerases by non-competitive inhibition of dNTPs. It is an antiviral agent used in the treatment of cytomegalovirus retinitis. It has activity against human herpesviruses and HIV.

BBF-05849

Foscarnet (4428-95-9)

Inquiry

Foscarnet is a pyrophosphate analog DNA polymerase inhibitor that has activity against several viruses, but is primarily used to treat CMV retinitis. Because it can cross the blood-brain barrier, it can be used to treat viral infections of the central nervous system.

BBF-05850

Foscarnet Sodium Hexahydrate is an antiviral drug used in the treatment of cytomegalovirus retinitis. It has inhibitory effect on viral DNA polymerase and reverse transcriptase.

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