Antiviral
| Catalog | Product Name / CAS / Description | Structure |
|---|---|---|
| BBF-04047 |
Ganciclovir (82410-32-0) Inquiry |
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Ganciclovir is an antiviral drug for feline herpesvirus type-1 with IC50 of 5.2 μM. |
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| BBF-05725 |
Megalomicin (129428-69-9) Inquiry |
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Megalomicins are a family of macrolide antibiotics produced by the soil bacterium Micromonospora megalomicea. They exhibit antiparasitic, antiviral and antibacterial activity, and are effective against both Gram-positive and Gram-negative bacteria. |
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| BBF-05848 |
Foscarnet sodium (63585-09-1) Inquiry |
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Foscarnet Sodium inhibits viral RNA polymerases, reverse transcriptases and DNA polymerases by non-competitive inhibition of dNTPs. It is an antiviral agent used in the treatment of cytomegalovirus retinitis. It has activity against human herpesviruses and HIV. |
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| BBF-05849 |
|
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Foscarnet is a pyrophosphate analog DNA polymerase inhibitor that has activity against several viruses, but is primarily used to treat CMV retinitis. Because it can cross the blood-brain barrier, it can be used to treat viral infections of the central nervous system. |
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| BBF-05850 |
Foscarnet Sodium Hexahydrate (34156-56-4) Inquiry |
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Foscarnet Sodium Hexahydrate is an antiviral drug used in the treatment of cytomegalovirus retinitis. It has inhibitory effect on viral DNA polymerase and reverse transcriptase. |
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| BBF-04651 |
Plitidepsin (137219-37-5) Inquiry |
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Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin shows potent anticancer activity against a large variety of cultured human cancer cells, inducing apoptosis by triggering mitochondrial cytochrome c release, initiating the Fas/DC95, JNK pathway and activating caspase 3 activation. This agent also inhibits elongation factor 1-a, thereby interfering with protein synthesis, and induces G1 arrest and G2 blockade, thereby inhibiting tumor cell growth. |
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| BBF-05847 |
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Favipiravir, also known as T-705 or Avigan, is an experimental antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses. Like some other experimental antiviral drugs (T-1105 and T-1106), it is a pyrazinecarboxamide derivative. Favipiravir is active against influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as other flaviviruses, arenaviruses, bunyaviruses and alphaviruses. Activity against enteroviruses and Rift Valley fever virus has also been demonstrated. |
