Bioactive by-products

Catalog Product Name / CAS / Description Structure
BBF-04031

Ketoconazole (65277-42-1)

Inquiry

Ketoconazole inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively. It is used primarily to treat fungal infections.

BBF-04375

Spirotryprostatin A is an indole alkaloid found in Aspergillus fumigatus fungus, which exhibits anti-mitotic activity.

BBF-05794

Aloeemodin (481-72-1)

Inquiry

Aloe-emodin is an interferon-inducing agent with IC50 of about 1 μg/mL for JEV and of about 0.33 μg/mL for EV71. Aloe-emodin has anti-tumor activity, antibacterial activity, immunosuppressive effect, and purgative effect. It is now widely used as a raw material for medicines and cosmetics.

BBF-04170

α-Mangostin (6147-11-1)

Inquiry

It was isolated from Garcinia mangostana Linn (Guttiferae). It is an anti-inflammatory agent. It can inhibit the activity of COX-2, an inhibitor of mutant IDH1 (IDH1-R132H).

BBF-05784

Menaquinone 7 (2124-57-4)

Inquiry

Menaquinone 7 is a form of vitamin K2, which includes nine related compounds. Menaquinone 7 is a long-chain menaquinone that is synthesized by Escherichia coli bacteria in the gut. It can be used as a supplement for bone health. Menaquinone 7 can be used as vitamin supplement in health care products.

BBF-04067

Withaferin A (5119-48-2)

Inquiry

Withaferin A, also referred to as D004, NSC 101088, used as an important medicinal herb for over 3000 years, is a steroidal lactone derived from Acnistus arborescens, Withania somnifera and other members of Solanaceae family. This natural product has wide range of pharmacological application comprising of anti-obesity, anti-inflammatory, anti-neoplastic, antiangiogenic, etc. It inhibits NF-kB activation and targets vimentin.

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