Bioactive by-products
Catalog | Product Name / CAS / Description | Structure |
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BBF-03340 | ||
PF-1092B is a nonsteroidal progesterone receptor ligand produced by Penicillium oblatum. It was shown to competitively inhibit [3H]-progesterone binding to porcine uteri cytosol preparations with IC50 of 2.2 x 10(2) nM. |
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BBF-03341 | ||
PF-1092C is a nonsteroidal progesterone receptor ligand produced by Penicillium oblatum. It was shown to competitively inhibit [3H]-progesterone binding to porcine uteri cytosol preparations with IC50 of 2.2 x 10(3) nM. |
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BBF-03342 | ||
PI-083 is a platelet aggregation inhibitor produced by Streptomyces matensis A-6621. It is active against gram-positive bacteria with MIC of 0.39-3.13 µg/mL. It inhibits platelet aggregation induced by ADP, Arachidonic Acid and collagen with MIC of 30.4, 1.9 and 3.8 µmol/L. It also inhibits KB cell growth with IC50 of 0.026 µmol/L. |
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BBF-03343 | ||
PI-200 is a platelet aggregation inhibitor produced by Streptomyces sp. A7498. It inhibited ADP-induced aggregation of rabbit platelets with IC50 of 3.8 x 10(-4) M. |
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BBF-03344 | ||
PI-201 is a platelet aggregation inhibitor produced by Streptomyces sp. A7498. It inhibited ADP-induced aggregation of rabbit platelets with IC50 of 7.1 x 10(-4) M. |
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BBF-03350 |
Oidiolactone A (90578-11-3) Inquiry |
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Oidiolactone A is a diterpenoid produced by Oidiodendron griseum CL37215. It inhibits LPS-induced IL-1β and TNF-α activity with IC50 values of 1.5 and 4.7 µmol/L. |
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BBF-03356 | ||
PS-990 is a metabolite produced by Acremonium sp. KY12702. It induced neurite formation in a murine neuroblastoma cell line, Neuro2A. |
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BBF-03357 | ||
R1128 A is a non-steroidal estrogen-receptor antagonist produced by Streptomyces sp. No. 1128. The IC50 value of R1128 A for partially purified rat uterine cytosol receptor was 11 x 10(-7) M. |
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BBF-03358 | ||
R1128 B is a non-steroidal estrogen-receptor antagonist produced by Streptomyces sp. No. 1128. The IC50 value of R1128 B for partially purified rat uterine cytosol receptor was 1.2 x 10(-7) M. |
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BBF-03359 | ||
R1128 C is a non-steroidal estrogen-receptor antagonist produced by Streptomyces sp. No. 1128. The IC50 value of R1128 C for partially purified rat uterine cytosol receptor was 2.6 x 10(-7) M. |
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BBF-03360 | ||
R1128 D is a non-steroidal estrogen-receptor antagonist produced by Streptomyces sp. No. 1128. The IC50 value of R1128 D for partially purified rat uterine cytosol receptor was 2.7 x 10(-7) M. |
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BBF-03361 | ||
R176502 is a bafilolide metabolite with potent antiproliferative activity, which is produced by Micromonospora sp. JS1035. It inhibits proliferation of MCF-7, HT-29, K562/C1000 and Malme-3M cells with IC50 values of 1.29 ± 0.35, 0.61 ± 0.04, 9.29 ± 7.35, 7.96 ± 2.75 nmol/L. |
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BBF-03362 | ||
RES-701-2 is an endothelin type B receptor antagonist produced by Streptomyces sp. RE-701. It selectively inhibits the ET-1 binding to endothelin type B receptor. |
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BBF-03363 | ||
RES-1149-1 is an endothelin type B receptor antagonist produced by Aspergillus sp. RE-1149. It selectively inhibits the ET-1 binding to endothelin type B receptor with IC50 value of 1.5 µmol/L. |
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BBF-03364 | ||
RES-1149-2 is an endothelin type B receptor antagonist produced by Aspergillus sp. RE-1149. It selectively inhibits the ET-1 binding to endothelin type B receptor with IC50 value of 20 µmol/L. |
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BBF-03365 | ||
RES-1214-1 is an endothelin type A receptor antagonist produced by Pestalotiopsis sp. RE-1214. It selectively inhibits the ET-1 binding to endothelin type A receptor with IC50 value of 1.5 µmol/L. |
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BBF-03366 | ||
RES-1214-2 is an endothelin type A receptor antagonist produced by Pestalotiopsis sp. RE-1214. It selectively inhibits the ET-1 binding to endothelin type A receptor with IC50 value of 20 µmol/L. |
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BBF-03372 | ||
RP-1551-1 is a compound in the class of azaphilone produced by Penicillium sp. SPC-21609. It inhibits the binding of PDGF AA to the extracellular domain of PDGF alpha-receptor potentially via reacting with amino groups on the alpha-receptor extracellular domain. |
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BBF-03373 | ||
RP-1551-2 is a compound in the class of azaphilone produced by Penicillium sp. SPC-21609. It inhibits the binding of PDGF AA to the extracellular domain of PDGF alpha-receptor. |
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BBF-03374 | ||
RP-1551-3 is a compound in the class of azaphilone produced by Penicillium sp. SPC-21609. It inhibits the binding of PDGF AA to the extracellular domain of PDGF alpha-receptor. |