Bioactive by-products

Antrimycin is a peptide antibiotic produced by Streptomyces xanthocidicus MG125-CF1.

Antrimycin is a peptide antibiotic produced by Streptomyces xanthocidicus MG125-CF1.

Aplasmomycin B is an antibiotic with antimalarial activity isolated from Streptomycete. Aplasmomycin has the activity of inhibiting gram-positive bacteria and mycobacteria, and has anti-protozoal effects.

Aplasmomycin C is an antibiotic with antimalarial activity isolated from Streptomycete. Aplasmomycin has the activity of inhibiting gram-positive bacteria and mycobacteria, and has anti-protozoal effects.

Asparenomycin B is a carbapenem antibiotic produced by Streptomyces tokunonensis sp. (PA-31088) and Srt.argenteolus (PA-39504). It has anti-gram-positive and negative bacteria activity, can inhibit a variety of β-lactamases, and also has an effect on β-lactamase-producing strains.

Asparenomycin C is a carbapenem antibiotic produced by Streptomyces tokunonensis sp. (PA-31088) and Srt.argenteolus (PA-39504). It has anti-gram-positive and negative bacteria activity, can inhibit a variety of β-lactamases, and also has an effect on β-lactamase-producing strains.

Berninamycin B is a peptide antibiotic produced by Streptomyces bernensis NRRL 3572.

Berninamycin C is a peptide antibiotic produced by Streptomyces bernensis NRRL 3572.

Brasiliquinone D is a benzo-onionquinone antibiotic produced by Nocardia brasiliensis.

Butirosin B is an aminoglycoside antibiotic produced by acillus circulans. It has activity against gram-positive bacteria, negative bacteria, and mycobacteria. It is not cross-resistant to gentamicin, and has an effect on some kanamycin-resistant bacteria.

Canescin is a metabolites produced by Pemcillum canescene.

Glidobactin A is an acyl peptide antibiotic produced by Pseudomonas sp. CB-3. It has activity against Candida, Aspergillus fumigatus and Trichophyton, but it is not effective against Candida albicans M-9 infection in mice.

Cepafungin III is an acyl peptide antibiotic produced by Pseudomonas sp. CB-3. It has activity against Candida, Aspergillus fumigatus and Trichophyton, but it is not effective against Candida albicans M-9 infection in mice.

Amifostine Thiol is a metabolite of Amifostine. Amifostine thiol activates p53 through a JNK-dependent signaling pathway.

An antimicrobial peptide (AMP) that is effective against a broad spectrum of bacteria including aerobic and anaerobic, gram-positive and gram-negative.

Spinosyn L is a component of Spinosyns, a group of compounds produced from fermentation of two species of Saccharopolyspora. It exhibits insecticidal activities against many commercially significant species that cause extensive damage to crops and other plants.

Spinosyn J is a component of Spinosyns, a group of compounds produced from fermentation of two species of Saccharopolyspora. It exhibits insecticidal activities against many commercially significant species that cause extensive damage to crops and other plants.

Voriconazole is an antifungal medication used to treat a number of fungal infections, including aspergillosis, candidemia, and esophageal candidiasis.

Dalbavancin is a semi-synthetic glycopeptide by introducing a positively charged lipophilic moiety in a previously unexplored region of the natural glycopeptide. This modification provides a longer in vivo half life, and improved in vitro activity against a variety of Gram-positive and multi-drug resistant isolates such as MRSA and MRSE.

Seramectin is a semi-synthetic abamectin derivative. Seramectin is an effective nematicide for the treatment of endoparasites and ectoparasites in domestic animals (especially cats and dogs). It can selectively bind to the chloride channel gated by the parasite's glutamate and disrupt neurotransmission, leading to paralysis and parasite death.