Enzyme inhibitors
| Catalog | Product Name / CAS / Description | Structure |
|---|---|---|
| BBF-03220 |
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B-5354b is a Sphingosine kinase (SPHK) inhibitor produced by SANK 71896. It has the activity of inhibiting SPHK with IC50 of 58 µmol/L. |
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| BBF-03221 |
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B-5354c is a Sphingosine kinase (SPHK) inhibitor produced by SANK 71896. It has the activity of inhibiting SPHK with IC50 of 38 µmol/L. |
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| BBF-03222 |
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B-90063 is an endothelin transferase (ECE) inhibitor produced by Blastobacter sp. SANK 71894. It has a strong inhibitory effect on human and rat ECE, with IC50 of 1.0 and 3.2 µmol/L, respectively. |
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| BBF-03224 |
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BE-10988 is a topoisomerase-II inhibitor produced by Str. sp. BA 10988. It has the activity of inhibiting P388 murine leukemia cells. It inhibits P388 (P388S), vincristine-doxorubicin-resistant P388 (P388/VCR) and doxorubicin-resistant P388 (P388/MDR) cells with IC50 (µmol/L) of 0.5, 0.4, 2.0, respectively. |
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| BBF-03227 |
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BE-18257 A is an endothelin binding inhibitor produced by Streptomyces misakiensis. |
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| BBF-03228 |
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BE-18257 B is an endothelin binding inhibitor produced by Streptomyces misakiensis. |
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| BBF-03231 |
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BE-23372M is a protein tyrosine kinase inhibitor produced by Rhizoctonia solani. It has strong inhibition of epidermal growth factor (EGF) receptor kinase activity. |
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| BBF-03239 |
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BE-40644 is an inhibitor of human Thioredoxin system produced by Actinoplanes sp. A40644. It can inhibit the growth of several tumor cells. |
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| BBF-03248 |
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BM2419-1 is a human topoisomerase I inhibitor produced by Paecilomyces sp. BM2419. It can selectively inhibit human topoisomerase with an IC50 of 0.3 ng/mL. |
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| BBF-03249 |
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BM2419-2 is a human topoisomerase I inhibitor produced by Paecilomyces sp. BM2419. It can selectively inhibit human topoisomerase with an IC50 of 0.6 ng/mL. |
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| BBF-03253 |
BMS-192548 (156368-93-3) Inquiry |
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BMS-192548 is a neuropeptide Y (NPY) receptor binding inhibitor produced by Aspergillus niger WB2346. It also has weak cytotoxicity, with an IC50 of 240 µmol/L for murine tumor cells M-109. |
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| BBF-03284 |
(E)-Pterulinic acid (190143-30-7) Inquiry |
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(E)-Pterulinic acid is a Coenzyme I: Coenzyme Q oxidoreductase inhibitor produced by Pterula sp. 82168. It has anti-yeast and filamentous fungus effect and has cytotoxic activity. |
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| BBF-03285 |
(Z)-Pterulinic Acid (530087-05-9) Inquiry |
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(Z)-Pterulinic Acid is a Coenzyme I: Coenzyme Q oxidoreductase inhibitor produced by Pterula sp. 82168. It has anti-yeast and filamentous fungus effect and has cytotoxic activity. |
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| BBF-03302 |
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NS is a mixture of polysaccharides produced by Streptomyces flavochromogenes 280, consisting of NS1~NS17. It has inhibitory effect against α-amylase and glucoamylase. |
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| BBF-03312 |
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OF4949 I is an aminopeptidase B produced by Penicillum rugulosum OF4949. |
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| BBF-03313 |
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OF4949 II is an aminopeptidase B produced by Penicillum rugulosum OF4949. |
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| BBF-03314 |
OF4949 III (107140-32-9) Inquiry |
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OF4949 III is an aminopeptidase B produced by Penicillum rugulosum OF4949. |
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| BBF-03315 |
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OF4949 IV is an aminopeptidase B produced by Penicillum rugulosum OF4949. |
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| BBF-03322 |
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P-725C is a prostaglandin synthetase inhibitor produced by Penicillum thomii. |
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| BBF-03368 |
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RK-286C is a protein kinase C (PKC) inhibitor produced by Streptomyces sp. RK-286. It inhibits PKC activity with IC50 of 3.0 µmol/L, as well as suppresses platelet aggregation induced by collagen and ADP. |
