Enzyme inhibitors

It is produced by the strain of Westerdykella multispora F50733. It is an immunologically active substance. It can strongly inhibit LPS-induced B cell proliferation and the production of B cell polyclonal IgM antibody, as well as T cell proliferation. The expression of IL-2 and IL-4 genes in Th cells was inhibited.

It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity.

It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity.

It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity.

It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity.

It is produced by the strain of Stachybitrys bisbyi. It can inhibit rat liver microsomal ACAT with IC50 of 1.7 μmol/L, inhibit plasma lecithin cholesterol acyltransferase (LCAT) with IC50 of 15.8 μmol/L, and inhibit cholesterol absorption in rats by 50% at 75 mg/kg.

It is produced by the strain of Streptomyces sp. C39. Gibbestatin B inhibits the expression of α-amylase induced by gibberellin in De-embryoned rice and barley (IC50 is 25-50 ppm, IC100 is 100-200 ppm), and has no anti-bacterial, anti-yeast and anti-fungal effects at 100 ppm (MIC, agar dilution method using bouillon agar for bacteria and Sabouraud agar for yeast and fungi).

It is produced by the strain of Gliocladium sp. FO-1513. It is a cholesterol acyltransferase (ACAT) inhibitor, and it can inhibit the formation of Appressorium on the hydrophobic surface of Magnaporthegrisea.

It is produced by the strain of Gliocladium sp. FO-1513. It is a cholesterol acyltransferase (ACAT) inhibitor.

It is produced by the strain of Gliocladium roseum HA190-95. It is a cholesterol acyltransferase (ACAT) inhibitor, and it can inhibit the formation of Appressorium on the hydrophobic surface of Magnaporthegrisea.

It is produced by the strain of Gliocladium roseum HA190-95. It is a cholesterol acyltransferase (ACAT) inhibitor, and it can inhibit the formation of Appressorium on the hydrophobic surface of Magnaporthegrisea.

It is produced by the strain of Gliocladium roseum HA190-95. It is a cholesterol acyltransferase (ACAT) inhibitor, and it can inhibit the formation of Appressorium on the hydrophobic surface of Magnaporthegrisea.

Glucoallosamidin A is a glycoside antibiotic produced by the strain of Streptomyces sp. SA-684. It can inhibit Chitinase activity.

Glucoallosamidin B is a glycoside antibiotic produced by the strain of Streptomyces sp. SA-684. It can inhibit Chitinase activity.

It is produced by the strain of Streptomyces purpurogeniscleroticus WC 71634, Nocardia vaccinii WC 65712. It is a glucokinase activator. It can reactivate the glucokinase inhibited by FAC with RC50 of 5.4 μmol/L.

It is produced by the strain of Streptomyces purpurogeniscleroticus WC 71634, Nocardia vaccinii WC 65712. It is a glucokinase activator. It can reactivate the glucokinase inhibited by FAC with RC50 of 4.6 μmol/L.

It is produced by the strain of Streptomyces griseoaurantiacus SANK43894. It has the activity of inhibiting cyclic adenosine monophosphate (cAMP) phosphodiesterase [EC 3.1.4.17] with IC50 0.16 X 10-6 mol/L (Extracted from rat brain). Griseolic acid A can stimulate the flow of glycogen and increase the blood sugar level in mice.

It is produced by the strain of Streptomyces griseoaurantiacus SANK43894. It has the activity of inhibiting cyclic adenosine monophosphate (cAMP) phosphodiesterase [EC 3.1.4.17] with IC50 0.16 X 10-6 mol/L (Extracted from rat brain).

It is produced by the strain of Streptomyces griseoaurantiacus SANK43894. It has the activity of inhibiting cyclic adenosine monophosphate (cAMP) phosphodiesterase [EC 3.1.4.17] with IC50 0.12 X 10-6 mol/L (Extracted from rat brain).

It is produced by the strain of Nannizzia gypsea var. incurvata IFO 9228. It can inhibit acylcoenzyme A, cholesterol acyltransferase (ACAT) activity, inhibit rat liver microbody ACAT with IC50 of 18 μmol/L, and its action is competitive with oleoyl-COA substrate, Ki value is 5.5 μmol/L. It also inhibits [14C] oleic acid from forming cholesterol esters with IC50 of 0.65 μmol/L.