Enzyme inhibitors

It is produced by the strain of Bipolaris zeicila. Cochlioquinone A1 inhibited DGAT with IC50 of 6.3 μg/mL.

It is produced by the strain of Streptomyces sp. OM-3209. Aggreceride had no antibacterial activity. Aggreceride A of 50 ㎍/ml inhibited thrombin-induced platelet aggregation of 92%. Aggreceride A of 25 ㎍/ml inhibited thrombin-induced platelet aggregation of 81%.

It is produced by the strain of Streptomyces sp. OM-3209. Aggreceride had no antibacterial activity.

It is produced by the strain of Streptomyces sp. OM-3209. Aggreceride had no antibacterial activity.

It is produced by the strain of Streptomyces griseoplanus. Corneas and Salmonella gallinarum were inhibited, and sarcoma cell 180 was moderately inhibited.

It is produced by the strain of Humicola sp. FO-5969. It has a weak inhibition of DGAT activity, and the IC50 of DGAT in rat liver microparticles is 124 ㎛ol/L, respectively. It has no toxicity to Raji cells and no antibacterial activity.

It is produced by the strain of Humicola sp. FO-2942. It inhibits DGAT activity, and the IC50 of rat liver microsomes DGAT is 19.2 X 10-6mol/L. It also inhibits triacylglycerol formation in intact Raji cells.

It is produced by the strain of Humicola sp. FO-2942. It inhibits DGAT activity, and the IC50 of rat liver microsomes DGAT is 51.6 X 10-6mol/L. It also inhibits triacylglycerol formation in intact Raji cells.

It is produced by the strain of Streptomyces sp MF-374-C4. It inhibits protein synthesis. On the synthetic medium (His-), it inhibits salmonella typhi TA 1535, and methionine could counteract its activity.

It is produced by the strain of Saccharothrix sp. AJ 9571. It can reduce the phosphorylation level of mitogen-activated protein kinase (MAPK)S6K. It induces apoptosis in Ras Ba/F3-V12 cells with an IC50 of 66 ng/mL, but not in IL-3 Ba/F3-V12 cells with 100 μg/mL.

It is produced by the strain of Actinornycete KP-3052. It has weak antibacterial activity. Inhibition of melanoma cell B16 production of melanin without affecting the growth of the cell, IC50 is 55 μmol/L.

It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase.

It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase.

It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase.

It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase.

It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase.

It is produced by the strain of Penicillum sp. FO-3929. It can inhibit PFTase. IC50 is 47.1 μmol/L.

It is produced by the strain of Penicillum sp. FO-3929. It can inhibit PFTase. IC50 is 13.3 μmol/L.

It is produced by the strain of Penicillum sp. FO-3929. It can inhibit PFTase. IC50 is 25.7 μmol/L.

It is produced by the strain of Dihetrospora catenulata SANK 10481, D. chlamidospora SANK 12181, Verticillum viveostratosum SANK 13358. It has the function of inhibiting Angiotensin converting enzyme.