Enzyme inhibitors

Aquastatin A is an adenosine triphosphatase inhibitor produced by Fusariumaquaeductuum.

Aquayamycin is a quinone antibiotic produced by Streptomyces misawanensis MA944-A5. Aquayamycin has weak antibacterial activity, prolongs the life of mice inoculated with Ehrlich ascites cancer, and inhibits tyrosine hydroxylase and monoamine oxidase.

Aranochlor A is an antibiotic produced by Pseudoarachniotus roseus (HIL Y-30499). It has activity against gram-positive bacteria such as Staphylococcus aureus, Bacillus subtilis and Micrococcus luteus and Saccharomyces cerevisiae. No effect on other Gram-negative bacteria and fungi.

Aranochlor B is an antibiotic produced by Pseudoarachniotus roseus (HIL Y-30499). It has activity against gram-positive bacteria such as Staphylococcus aureus, Bacillus subtilis and Micrococcus luteus and Saccharomyces cerevisiae. No effect on other Gram-negative bacteria and fungi.

Aranotin is an antibiotic produced by the shell of the cyst Arachniotus aureus. Aranotin inhibits viral RNA synthesis by impeding the activity of RNA-dependent RNA polymerase. Aranotin have antiviral effects and can inhibit the formation of plaques of type I, II, and III poliovirus.

Arborcandins are 1,3-β-glucan synthase inhibitors produced by the filamentous fungus SANK 17397.

Arborcandins are 1,3-β-glucan synthase inhibitors produced by the filamentous fungus SANK 17397.

Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively.

Argimicin A is a potent anti-cyanobacterial compound produced by one of algae-lysing bacteria, Sphingomonas sp.

Argimicin B is a pentapeptide antibiotic produced by Sphingomonas sp.

Argimicin C is a pentapeptide antibiotic produced by Sphingomonas sp.

Argyrin A has weak antibacterial activity, but has obvious effects on Pseudomonas bacteria. It can inhibit the growth of mammalian cell culture.

Argyrin B can strongly inhibit the murine mixed lymphocyte reaction (MLR) and is an inhibitor of antibody formation independent of T cells.

Arisugacin is an acetylcholinesterase (AChE) inhibitor produced by Penicillum sp. FO-4259.

Arisugacin B is an acetylcholinesterase (AChE) inhibitor produced by Penicillum sp. FO-4259.

Arisugacin H is an acetylcholinesterase (AChE) inhibitor produced by Penicillum sp. FO-4260.

Aselacin A is a substance produced by Acremonium sp. AB 2093T-194 and AB 2068-51 that inhibits the binding of endothelin (en-dothelin) to its receptor. It has the effect of inhibiting the binding of endothelin to its receptor.

Aselacin B is a substance produced by Acremonium sp. AB 2093T-194 and AB 2068-51 that inhibits the binding of endothelin (en-dothelin) to its receptor. It has the effect of inhibiting the binding of endothelin to its receptor.

Aselacin C is a substance produced by Acremonium sp. AB 2093T-194 and AB 2068-51 that inhibits the binding of endothelin (en-dothelin) to its receptor. It has the effect of inhibiting the binding of endothelin to its receptor.

Ashimycin A is an aminoglycoside antibiotic produced by Streptomyces griseus FT3-4. It has a broad-spectrum antibacterial activity, but is lower than streptomycin.