Raw Materials of Healthcare Products
| Catalog | Product Name / CAS / Description | Structure |
|---|---|---|
| BBF-05816 |
2'-Fucosyllactose (41263-94-9) Inquiry |
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2'-Fucosyllactose is produced by microbial fermentation of transgenic Escherichia coli strains. It is a human milk sugar oligosaccharide used in infant nutrition. |
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| BBF-05817 |
Astaxanthin (472-61-7) Inquiry |
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Astaxanthin is a carotenoid pigment found mostly in animal organisms, but also occurring in plants. It is thought to be the precursor of astacin. It is a potent lipid-soluble antioxidant. It has broad application prospects in health products, medicine, cosmetics, food additives and aquaculture. Astaxanthin is a natural antioxidant with the strongest antioxidant and anti-aging ability in nature, and its antioxidant capacity is much higher than VE and β-carotene. It significantly enhances mitochondrial activity required for cell recombination and effectively protects the skin from UVA, UVB and blue light damage. |
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| BBF-05819 |
Eicosapentaenoic Acid (10417-94-4) Inquiry |
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Eicosapentaenoic acid (EPA) is an omega-3 fatty acid found in fish oil. It acts as a precursor to prostaglandin-3 and thromboxane-3 families. EPA decreases serum lipid concentration, reduces the risk of cardiovascular disorders and suppresses platelet aggregation. |
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| BBF-05820 |
Vitamin B12 (68-19-9) Inquiry |
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Vitamin B12 is a water-soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. |
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| BBF-05821 |
Coenzyme A (85-61-0) Inquiry |
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Coenzyme A is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP. Coenzyme A plays important roles in many metabolic pathways, including the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. About 4% of cellular enzymes utilize CoA as a substrate. |
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| BBF-05871 |
Calcifediol (19356-17-3) Inquiry |
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Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It also suppresses PTH secretion and mRNA (ED50=2 nM). |
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| BBF-05872 |
Vitamin K1 (84-80-0) Inquiry |
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Vitamin K1 is a fat-soluble vitamin that occurs widely in green plants, algae, photosynthetic bacteria. Vitamin K1 serves as a precursor to vitamin K2 and is essential for the synthesis of proteins required for blood-clotting, bone metabolism, and cell growth. It is commonly used in dietary supplement for the treatment of bleeding disorders. |
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| BBF-05873 |
DL-Cystine (923-32-0) Inquiry |
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DL-Cystine is a non-essential amino acid used as a nutritional and dietary supplement. |
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| BBF-05874 |
Soya Lecithin (8030-76-0) Inquiry |
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Soya Lecithin has emulsifying and lubricating properties and can be used as a surfactant. It is an antioxidant with free radical scavenging properties. Soya Lecithin has strong surface activity and colloidal properties, and plays an important role in cell metabolism and cell membrane permeability regulation. Soya Lecithin has good moisture and permeability to human skin, with antioxidant, antistatic, emulsifying, dispersing, wetting, penetrating, moisturizing, conditioning, softening, moisturizing and hair-softening functions. |
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| BBF-05875 |
Vitamin D3 (67-97-0) Inquiry |
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Cholecalciferol is a naturally occurring form of vitamin D which is obtained from dietary sources, such as fish, or through the conversion of 7-dehydrocholesterol by ultraviolet light. It is subsequently metabolized to 25-hydroxyvitamin D3 and the active form 1,25-dihydroxyvitamin D3 by cytochrome P450 isoforms in the liver. It could prevent proliferation of cancer cells. |
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| BBF-05887 | ||
Shinorine, a mycosporine-like amino acid (MAA) and an analog of porphyra-344, is a small molecule sunscreen produced by some bacteria with antioxidant, anti-UV, and sun protection properties. Shinorine ameliorates chromium-induced toxicity in zebrafish hepatocytes through facultatively activating the Nrf2-Keap1-ARE pathway. Both porphyrin-334 and Shinorine antioxidants and direct antagonists of Keap1-Nrf2 binding. Shinorine may be an effective drug to prevent or delay the progression of a variety of degenerative aging diseases. |
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| BBF-05731 |
Pyrroloquinoline quinone disodium salt (122628-50-6) Inquiry |
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The disodium salt form of Pyrroloquinoline quinone which is a cofactor related to the enzyme-catalyzed redox reactions glucose and methanol dehydrogenase. Pyrroloquinoline quinone disodium salt is isolated from cultures of methylotropic bacteria and tissues of mammals. |
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| BBF-05876 |
β-Carotene (7235-40-7) Inquiry |
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β-Carotene is an organic compound and classified as a terpenoid. It is a precursor (inactive form) of vitamin A. β-carotene is widely used in the food industry, feed industry, medicine and cosmetics industry. β-carotene is an important part of the non-enzymatic defense mechanism against free radicals, which can effectively slow down aging while protecting against UV damage. In addition, it can whiten spots and have blue light protection effect. It can be widely used in anti-aging, wrinkle removal, firming and tender skin, whitening, light spot, sun protection, anti-blue light and other products, and it is compatible with lotion cream formula, gel formula and water formula. |
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| BBF-05877 |
Coenzyme Q10 (303-98-0) Inquiry |
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Coenzyme Q10 (ubiquinone, ubidecarenone, coenzyme Q) is a component of the electron transport chain and participates in aerobic cellular respiration. Coenzyme Q10 is widely found in the mitochondria of the whole body. It has a stronger antioxidant function than vitamin C and vitamin E, can effectively remove free radicals, and has good anti-aging, whitening, and moisturizing functions. It can be widely used in anti-aging and wrinkle-removing, whitening and lightening spots, moisturizing and moisturizing, firming and tenderizing skin, sunscreen repair products, and it is compatible with lotion cream formula, gel formula, and water formula. |
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| BBF-05822 |
Glutathione (70-18-8) Inquiry |
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Glutathione (GSH) is an endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione may decrease the concentrations of inflammatory cytokines (IL-6, IL-18), and neutrophils in lung tissue, increase the level of serum Ca2+, and be useful for the treatment of ANP. Glutathione can be used not only as medicine but also as a base material for functional foods. It is widely used in functional foods for delaying aging, enhancing immunity, and anti-tumor. Glutathione is the main ingredient in ''whitening needle'' injections, and it is also the main ingredient in many beauty products on the market. |
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| BBF-05818 |
Docosahexaenoic acid (6217-54-5) Inquiry |
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Docosahexaenoic acid (DHA) is an omega-3 fatty acid found in fish oil and a major component of excitable membranes of the retina and brain. It decreases the level of blood triglycerides and reduces the risk of cardiovascular disorders. |
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| BBF-04029 |
Folic acid (59-30-3) Inquiry |
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Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate. The combined use of enalapril and folic acid, compared with enalapril alone, significantly reduced the risk of first stroke. High folic acid intakes and MTHFR gene variations seem not to be associated with helping women to achieve pregnancy during or after fertility treatment. |
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| BBF-05784 |
Menaquinone 7 (2124-57-4) Inquiry |
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Menaquinone 7 is a form of vitamin K2, which includes nine related compounds. Menaquinone 7 is a long-chain menaquinone that is synthesized by Escherichia coli bacteria in the gut. It can be used as a supplement for bone health. Menaquinone 7 can be used as vitamin supplement in health care products. |
Find out more with our brochure of raw materials of healthcare products.
BOC Sciences provides high-quality nutritional products and innovative solutions to customers in the field of nutritional and health products around the world through sustainable microbial manufacturing, biotechnology-based, integrated industrial culture optimization, precision fermentation, and efficient separation and purification technologies. We are committed to using advanced biotechnology to produce more efficient, safe, and sustainable raw materials for healthy products to meet the growing demand of the market.
Classification of fermentation health raw materials
The microbial fermentation process can produce a variety of valuable metabolites, including amino acids, vitamins, fatty acids, natural pigments, etc., which can provide richer nutritional support and create better health products. A variety of valuable metabolites can be produced during microbial fermentation, including amino acids, vitamins, fatty acids, natural pigments, etc. These metabolites not only provide rich nutritional support for nutraceuticals, but also create innovative products with specific health functions.
Vitamins
While humans are unable to synthesize multivitamins, adequate dietary intake is essential to avoid deficiencies. Fermentation is an alternative strategy to ensure adequate intake of essential vitamins. Such as riboflavin (vitamin B2), folic acid (vitamin B9), cobalamin (B12), or vitamin K, which are involved in several essential human functions, such as nucleic acid synthesis, cellular metabolism, cardiovascular and bone health, and protection against oxidative stress.
Vitamin B Complex: These include vitamin B1 (thiamine), vitamin B2 (riboflavin), vitamin B6 (pyridoxine), vitamin B12 (cobalamin), and more, which play a key role in energy metabolism, nervous system health, and red blood cell production.
Vitamin K2: Vitamin K2 is a menadione series of compounds, a menadione series of compounds produced by the fermentation of Bacillus natto, and is an essential human endogenous high-activity vitamin, which plays an important role in bone health and cardiovascular health. And vitamin K2 produced by fermentation technology has high bioavailability.
PQQ disodium salt: Pyrroloquinoline quinone (PQQ) has strong antioxidant and neuroprotective effects, and its purity and stability can be guaranteed by fermentation production. At present, Methylovorus sp.MP688 has been widely used in the production of PQQ.
Amino acids and bioactive peptides
Fermentation engineering can produce a variety of amino acids and bioactive peptides that help boost immunity, and antioxidants, improve sleep, and promote muscle growth, among other things.
DL-Cystine: As an important amino acid, cystine has antioxidant and detoxifying effects and is commonly used in skin care products and health supplements.
γ-aminobutyric acid (GABA): GABA is a four-carbon non-protein amino acid that is a major inhibitory neurotransmitter in the central nervous system with antihypertensive, diuretic, and sedative effects, as well as antidiabetic effects. Lactic acid strains can produce GABA during fermentation.
ACE inhibitory peptides: It is the most studied bioactive peptide, ACE inhibitory peptides are often described during milk fermentation, such as valine-prolyl-proline (VPP) and isoleucyl-prolyl-proline (IPP), which are considered strategies for the treatment of hypertension.
Fatty acids
Fermentation technology enables the production of high-value fatty acids, such as CLA and EPA, which play an important role in promoting brain development and cardiovascular health.
Conjugated Linoleic Acid (CLA): CLA has received high attention for its beneficial properties and protective effects against a variety of diseases, such as atherosclerosis, obesity, chronic inflammatory diseases, and cancer. Bifidobacteria, Enterococci, and Streptococcus, among others, have been identified as CLA producers.
Eicosapentaenoic acid (EPA): Eicosapentaenoic acid (EPA) is an unsaturated fatty acid that is one of several omega-3 fatty acids commonly used by the body and cannot be synthesized by the body. EPA can be produced by fermentation of microorganisms such as Yeyeria lipolystica. EPA can reduce triglycerides and total cholesterol in the human blood, improve blood circulation, and help reduce inflammation and improve cardiovascular health.
Natural pigments
Fermentation technology enables the production of natural pigments, which not only add color to foods and health products, but also have health benefits such as antioxidants.
β-Carotene: β-Carotene is an orange-colored fat-soluble compound, an important antioxidant that helps maintain healthy skin and eyes. Natural beta-carotene, which is mainly extracted from plants and algae, cannot meet the growing market demand, while the production of beta-carotene by microbial fermentation is a promising alternative due to its high efficiency and environmental friendliness.
Astaxanthin: It is a carotenoid that has a powerful antioxidant effect, which can neutralize free radicals and delay aging. It can be synthesized by fermentation of E. coli and saccharomyces cerevisiae.
Glucalogue
Fermentation can also produce some ingredients with special functions, which have a wide range of applications in health supplements.
2'-Fucosyllactose(2'-FL): An important human milk oligosaccharide that contributes to intestinal health in infants. Microbial synthesis of 2'-FL has the advantages of easy large-scale production and the use of inexpensive raw materials as substrates. At present, the most important industrially produced strain of 2'-FL is Escherichia coli, and other food-safe strains such as Saccharomyces cerevisiae and Bacillus subtilis have also been modified to produce 2'-FL, and have achieved certain results.
Coenzyme A: Coenzyme A is a cofactor that plays a key role in energy metabolism in the body and can be obtained by microbial fermentation, acting as an acyl carrier and carbonyl activator in the citric acid cycle and fatty acid metabolism.
Features of our products
Non-GMO strains, non-animal origin: We use non-GMO microbial strains for fermentation to ensure the naturalness and safety of our products.
Mature medium formulation and dynamic control: Through scientific medium formulation and dynamic control of the fermentation process, the consistency and high quality of the product are ensured.
Physical separation and concentration technology: All extracts are made of physical separation and concentration technology, which is solvent-free and extracts residues to ensure the purity of the product.
100% Natural Fermentation Origin: All our products are derived from a natural fermentation process and meet the needs of modern health products.
Product security
The health products and raw materials we provide to our customers worldwide are produced in a fully enclosed and controlled process certified by FSCC 22000. These supplements are Kosher, HALAL, GRAS, and HACCP certified. Our products such as Vitamin K2 and PQQ disodium salt have undergone strict quality control to ensure their safety and efficacy.
Reference
- Diez-Ozaeta, Inaki, and Oihana Juaristi Astiazaran. Fermented foods: An update on evidence-based health benefits and future perspectives. Food Research International 156 (2022): 111133.
