10-Hydroxyundeca-2,4,6,8-tetraynamide

10-Hydroxyundeca-2,4,6,8-tetraynamide

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10-Hydroxyundeca-2,4,6,8-tetraynamide
Category Antibiotics
Catalog number BBF-01032
CAS 83475-37-0
Molecular Weight 185.18
Molecular Formula C11H7NO2

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Description

10-Hydroxyundeca-2,4,6, 8-tetraynamide is a polyacetylene antibiotic produced by Mycena viridimarginata 7638. It has anti-gram-positive bacteria, negative bacteria, yeast, fungus activity and cytotoxicity.

Specification

Synonyms 10-Hydroxy-undeca-2,4,6,8-tetraynamide
Canonical SMILES CC(C#CC#CC#CC#CC(=O)N)O
InChI InChI=1S/C11H7NO2/c1-10(13)8-6-4-2-3-5-7-9-11(12)14/h10,13H,1H3,(H2,12,14)
InChI Key MGQYNHBGKXGGRA-UHFFFAOYSA-N

Properties

Antibiotic Activity Spectrum Gram-positive bacteria; Gram-negative bacteria; fungi; yeast
Boiling Point 358.3°C at 760 mmHg
Density 1.303 g/cm3

Reference Reading

1. Antibiotics from Basidiomycetes. XVI. Antimicrobial and cytotoxic polyines from Mycena viridimarginata Karst
J Bäuerle, T Anke, R Jente, F Bosold Arch Microbiol. 1982 Aug;132(2):194-6. doi: 10.1007/BF00508730.
Two new biologically active polyines were isolated from cultures of the fungus Mycena viridimarginata. Their structures were elucidated by spectroscopic and chemical methods as 10-hydroxy-undeca-2,4,6,8-tetraynamide (1) and 3,4,13-trihydroxy-tetradeca-5,7,9,11-tetraynoic acid-gamma-lactone (2). The main component (1) is highly antibiotically active and cytotoxic.

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