13-Deoxycarminomycin
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Category | Antibiotics |
Catalog number | BBF-00836 |
CAS | 76034-18-9 |
Molecular Weight | 499.51 |
Molecular Formula | C26H29NO9 |
Purity | ≥95% |
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Capabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
13-Deoxycarminomycin, an antineoplastic agent and a bacterial metabolite, is a cytotoxic anthracycline antibiotic produced by Streptomyces peucetius var. carminatus (a biochemical mutant of Streptomyces peucetius var. caesius). It has activity against Gram-positive bacteria, Gram-negative bacteria, tumors and P-388 murine leukemia.
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Related CAS | 76036-24-3 (monohydrochloride) |
Synonyms | Antibiotic D 788-11; R 20X; 13-Deoxocarminomycin; (8S)-10α-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-ethyl-7,8,9,10-tetrahydro-1,6,8α,11-tetrahydroxy-5,12-naphthacenedione; 13-Deoxocarminomycin I; (1S,3S)-3-Ethyl-3,5,10,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-8-ethyl-1,6,8,11-tetrahydroxy-, (8S-cis)-; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, (8S,10S)- |
Storage | Store at -20°C under inert atmosphere |
IUPAC Name | (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-9-ethyl-4,6,9,11-tetrahydroxy-8,10-dihydro-7H-tetracene-5,12-dione |
Canonical SMILES | CCC1(CC(C2=C(C1)C(=C3C(=C2O)C(=O)C4=C(C3=O)C=CC=C4O)O)OC5CC(C(C(O5)C)O)N)O |
InChI | InChI=1S/C26H29NO9/c1-3-26(34)8-12-18(15(9-26)36-16-7-13(27)21(29)10(2)35-16)25(33)20-19(23(12)31)22(30)11-5-4-6-14(28)17(11)24(20)32/h4-6,10,13,15-16,21,28-29,31,33-34H,3,7-9,27H2,1-2H3/t10-,13-,15-,16-,21+,26-/m0/s1 |
InChI Key | UHYFCDBUKBJSFA-JYFLSIMMSA-N |
Appearance | Very Dark Green to Black Solid |
Antibiotic Activity Spectrum | Gram-positive bacteria; Gram-negative bacteria; neoplastics (Tumor) |
Boiling Point | 713.1±60.0°C at 760 mmHg |
Melting Point | 171-175°C (dec.) |
Density | 1.6±0.1 g/cm3 |
Solubility | Soluble in Chloroform (Slightly), DMSO (Slightly) |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
