15-Deoxy-15-oxolankamycin
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-01354 |
| CAS | |
| Molecular Weight | 830.99 |
| Molecular Formula | C42H70O16 |
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Description
It is produced by the strain of Streptomyces violaceoniger. 15-Deoxy-15-oxolankamycin has a weak anti-gram-positive effect, with anti-Staphylococcus aureus activity equal to half that of Lankamycin.
Properties
| Appearance | Colorless Acicular Crystalline |
| Antibiotic Activity Spectrum | Gram-positive bacteria |
| Melting Point | 139-141°C |
Reference Reading
1. Biotransformation of lankamycin, darcanolide, and 11-acetyllankolide by a blocked mutant of the erythromcyin producing organism Streptomyces erythreus
A W Goldstein, R S Egan, S L Mueller, J R Martin, W Keller-Schierlein J Antibiot (Tokyo). 1978 Jan;31(1):63-9. doi: 10.7164/antibiotics.31.63.
The biotransformation of lankamycin and congeners darcanolide and 11-acetylankolide by a blocked mutant of the erythromycin-producing organism Streptomyces erythreus, which cannot synthesize erythromycin without supplementation with erythromycin precursors, was investigated. Darcanolide and 11-acetyllankolide were converted into the corresponding 15-deoxy-15-oxo derivatives. Lankamycin was transformed to 15-deoxy-15-oxolankamycin, 4''-deacetyl-15-deoxy-15-oxolankamycin and 3'-de-O-methylankamycin. None of the derivatives possessed high antimicrobial activity.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
