(-)-2-(2-Hydroxyethyl)clavam

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Category Antibiotics
Catalog number BBF-00997
CAS 79416-52-7
Molecular Weight 157.17
Molecular Formula C7H11NO3

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Description

(-)-2-(2-Hydroxyethyl)clavam is an oxypenicillane antibiotic produced by Streptomyces antibiotcus var. antibioticus Tu 1718. It has anti-fungal and weak anti-Gram-positive and negative bacteria activity.

Specification

Synonyms Hydroxyethylclavam; 2-Hydroxyethylclavam; 3-(2-hydroxyethyl)-4-oxa-1-azabicyclo[3.2.0]heptan-7-one
IUPAC Name (3S,5S)-3-(2-hydroxyethyl)-4-oxa-1-azabicyclo[3.2.0]heptan-7-one
Canonical SMILES C1C2N(C1=O)CC(O2)CCO
InChI InChI=1S/C7H11NO3/c9-2-1-5-4-8-6(10)3-7(8)11-5/h5,7,9H,1-4H2/t5-,7-/m0/s1
InChI Key UEGDICIJUUEIOL-FSPLSTOPSA-N

Properties

Appearance Colorless Oil
Antibiotic Activity Spectrum Gram-positive bacteria; Gram-negative bacteria; fungi
Boiling Point 350.2±35.0 °C at 760 mmHg
Melting Point 157.17°C
Density 1.4±0.1 g/cm3

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