2-(acetylamino)benzenecarboxamide
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| Category | Antibiotics |
| Catalog number | BBF-03526 |
| CAS | 33809-77-7 |
| Molecular Weight | 178.19 |
| Molecular Formula | C9H10N2O2 |
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Description
2-(acetylamino)benzenecarboxamide is an antifungal antibiotic isolated from Streptomyces aurantiogriseus NPO-101.
Specification
| Synonyms | 2-(acetylamino)-benzamide; 2-(acetylamino)benzamide; 2'-carbamoyl-acetanilide; 2'-carbamoylacetanilide; NP 101A; NP-101A |
| IUPAC Name | 2-acetamidobenzamide |
| Canonical SMILES | CC(=O)NC1=CC=CC=C1C(=O)N |
| InChI | InChI=1S/C9H10N2O2/c1-6(12)11-8-5-3-2-4-7(8)9(10)13/h2-5H,1H3,(H2,10,13)(H,11,12) |
| InChI Key | WFKPHYKFAOXUTI-UHFFFAOYSA-N |
Properties
| Appearance | White Powder |
| Antibiotic Activity Spectrum | fungi |
| Melting Point | 160-163°C |
Reference Reading
1. Iodixanol (Optiprep), an improved density gradient medium for the iso-osmotic isolation of rat liver peroxisomes
P P Van Veldhoven, E Baumgart, G P Mannaerts Anal Biochem. 1996 May 15;237(1):17-23. doi: 10.1006/abio.1996.0194.
The suitability of Iodixanol {5,5'-[(2-hydroxy-1, 3-propanediyl)-bis(acetylamino)] bis-[N,N'-bis(2, 3-dihydroxypreopyl-2,4,6-triiodo-1,3-benzenecarboxamide)]}, a nonionic iodinated compound with a molecular weight of 1550, for the isolation of peroxisomes from rat liver was investigated. Centrifugation of light mitochondrial fractions in 20 to 40% (w/v) Iodixanol gradients, made iso-osmotic by the addition of sucrose, resulted in an excellent separation of peroxisomes from the remaining organelles, which were not able to enter the gradient. Peroxisomes banded around 30% (w/v) Iodixanol (d approximately 1.175) and, as revealed by marker enzyme analysis, were enriched 35- to 40-fold. Morphological examination of the peroxisomal fractions confirmed the near absence of other organelles and revealed structurally well-preserved peroxisomes. Free cores, also present in the starting fractions, migrated to higher densities and were trapped on a cushion. No interference of Iodixanol with marker enzyme determinations was observed, except for the UV-metric determination of urate oxidase and for the analysis of protein.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
