23-O-Desmycinosyl-tylosin

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23-O-Desmycinosyl-tylosin
Category Antibiotics
Catalog number BBF-01699
CAS 79592-92-0
Molecular Weight 741.90
Molecular Formula C38H63NO13
Purity ≥85.0%

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Description

Tylosin EP Impurity A, an impurity of Tylosin, is a macrolide antibiotic produced by Streptomyces fradiae GS76 and GS48. It has anti-gram-positive bacteria and weak anti-gram-negative bacteria and mycoplasma activity.

Specification

Related CAS 81307-29-1 (Deleted CAS) 85185-04-2 (Deleted CAS) 115033-50-6 (Deleted CAS)
Synonyms 22-O-Demycinosyltylosin; 23-O-Demycinosyltylosin; Demycinosyltylosin; Tylosin EP Impurity A; 23-De(mycinosyl)tylosin; Antibiotic YO 9010; BRN 4649503; Tylosin, 23-O-de(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)-; 23-O-De(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)tylosin; 23-Demycinosyltylosin
Storage Store in a cool and dry place and at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
IUPAC Name 2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-(hydroxymethyl)-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
Canonical SMILES CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)C)CO
InChI InChI=1S/C38H63NO13/c1-10-29-26(19-41)15-20(2)11-12-27(42)21(3)16-25(13-14-40)34(22(4)28(43)17-30(44)50-29)52-37-33(45)32(39(8)9)35(23(5)49-37)51-31-18-38(7,47)36(46)24(6)48-31/h11-12,14-15,21-26,28-29,31-37,41,43,45-47H,10,13,16-19H2,1-9H3/b12-11+,20-15+/t21-,22+,23-,24+,25+,26-,28-,29-,31+,32-,33-,34-,35-,36+,37+,38-/m1/s1
InChI Key ZVOOGERIHVAODX-LXKXJHEOSA-N

Properties

Appearance White Crystalline Powder
Antibiotic Activity Spectrum Gram-positive bacteria; Gram-negative bacteria; mycoplasma
Boiling Point 890.7±65.0°C at 760 mmHg
Melting Point 138-142°C
Density 1.23±0.1 g/cm3
Solubility Soluble in DMSO

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