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3-Ethyl-1,3-dihydro-3-methoxy-2H-indol-2-one

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Category Others
Catalog number BBF-00877
CAS 66424-33-7
Molecular Weight 191.23
Molecular Formula C11H13NO2

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Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

3-Ethyl-1,3-dihydro-3-methoxy-2H-indol-2-one is an indole derivative produced by Streptomyces antibioticus X-14547. It has anti-gram-positive and negative bacteria activity.

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IUPAC Name 3-ethyl-3-methoxy-1H-indol-2-one
Canonical SMILES CCC1(C2=CC=CC=C2NC1=O)OC
InChI InChI=1S/C11H13NO2/c1-3-11(14-2)8-6-4-5-7-9(8)12-10(11)13/h4-7H,3H2,1-2H3,(H,12,13)
InChI Key ICBZGIGZAFEKFH-UHFFFAOYSA-N
Antibiotic Activity Spectrum Gram-positive bacteria; Gram-negative bacteria
Melting Point 179°C
1. Isolation and characterization of antibiotic X-14547A, a novel monocarboxylic acid ionophore produced by Streptomyces antibioticus NRRL 8167
J W Westley, R H Evans Jr, L H Sello, N Troupe, C M Liu, J F Blount J Antibiot (Tokyo). 1979 Feb;32(2):100-7. doi: 10.7164/antibiotics.32.100.
A novel carboxylic acid ionophore, antibiotic X-14547A, closely related to the polyether antibiotics has been isolated along with four other metabolites from fermented cultures of a new strain of Streptomyces antibioticus. The structure, determined by X-ray analysis of the R(+)-1-amino-1-(4-bromophenyl)-ethane salt contained pyrrole carbonyl and trans-butadienyl chromophores in addition to the unusual tetrahydroindane bicyclic ring system. A second novel metabolite was identified as 3-ethyl-1,3-dihydro-3-methoxy-2H-indol-2-one.

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