4''-α-D-Glucopyranosylkanamycin B

4''-α-D-Glucopyranosylkanamycin B

Catalog number:

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

It is produced by the strain of Streptomyces kanamyceticus A-4-6. It's an aminoglycoside antibiotic. It has anti-gram positive bacteria and negative bacteria activity.

4''-α-D-Glucopyranosylkanamycin B
  • Specification
  • Reference Reading
  • Recommended Products
Catalog Number BBF-01798
CAS 84123-75-1
Description It is produced by the strain of Streptomyces kanamyceticus A-4-6. It's an aminoglycoside antibiotic. It has anti-gram positive bacteria and negative bacteria activity.
Molecular Formula C24H47N5O15
Molecular Weight 645.65
Antibiotic Activity Spectrum Gram-positive bacteria; Gram-negative bacteria
Synonyms 4''-alpha-D-Glucopyranosylkanamycin B; D-Streptamine, O-2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4)-O-(O-alpha-D-glucopyranosyl-(1-4)-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-2-deoxy-; 4,6-Diamino-3-[(3-amino-3-deoxy-4-O-hexopyranosylhexopyranosyl)oxy]-2-hydroxycyclohexyl 2,6-diamino-2,6-dideoxyhexopyranoside
IUPAC Name 2-[4-amino-6-[4,6-diamino-3-[3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
Canonical SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)OC3C(C(C(C(O3)CO)O)O)O)N)O)O)OC4C(C(C(C(O4)CN)O)O)N)N
InChI InChI=1S/C24H47N5O15/c25-2-7-12(32)14(34)11(29)22(39-7)42-19-5(26)1-6(27)20(18(19)38)43-23-15(35)10(28)21(9(4-31)41-23)44-24-17(37)16(36)13(33)8(3-30)40-24/h5-24,30-38H,1-4,25-29H2
InChI Key STAYKUHDGMBJKQ-UHFFFAOYSA-N
Boiling Point 958.5 °C at 760 mmHg
Melting Point 253 °C (dec.)
Purity 95%
Density 1.66 g/cm3
Appearance White Powder
1.The aminoglycoside antibiotics. I. Synthesis and biological evaluation of an analog of gentamicin.
Sitrin RD, Cooper DJ, Weisbach JA. J Antibiot (Tokyo). 1977 Oct;30(10):836-42.
The synthesis of 2-deoxy-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythrohexopyranosyl)-6-O-(3-deoxy-3-methylamino-alpha-D-xylopyranosyl)-D-streptamine (1), an analog of gentamicin A, from diideoxyneamine and methyl 3-methylamino-3-deoxy-beta-D-xylopyranoside is described. The product was characterized by its 13C nmr spectrum and was found to exhibit broad spectrum antibacterial activity.

-------

Get In Touch

Verification code
Inquiry Basket