4''-α-D-Glucopyranosylkanamycin B
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-01798 |
| CAS | 84123-75-1 |
| Molecular Weight | 645.65 |
| Molecular Formula | C24H47N5O15 |
| Purity | 95% |
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Description
It is produced by the strain of Streptomyces kanamyceticus A-4-6. It's an aminoglycoside antibiotic. It has anti-gram positive bacteria and negative bacteria activity.
Specification
| Synonyms | 4''-alpha-D-Glucopyranosylkanamycin B; D-Streptamine, O-2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4)-O-(O-alpha-D-glucopyranosyl-(1-4)-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-2-deoxy-; 4,6-Diamino-3-[(3-amino-3-deoxy-4-O-hexopyranosylhexopyranosyl)oxy]-2-hydroxycyclohexyl 2,6-diamino-2,6-dideoxyhexopyranoside |
| IUPAC Name | 2-[4-amino-6-[4,6-diamino-3-[3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol |
| Canonical SMILES | C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)OC3C(C(C(C(O3)CO)O)O)O)N)O)O)OC4C(C(C(C(O4)CN)O)O)N)N |
| InChI | InChI=1S/C24H47N5O15/c25-2-7-12(32)14(34)11(29)22(39-7)42-19-5(26)1-6(27)20(18(19)38)43-23-15(35)10(28)21(9(4-31)41-23)44-24-17(37)16(36)13(33)8(3-30)40-24/h5-24,30-38H,1-4,25-29H2 |
| InChI Key | STAYKUHDGMBJKQ-UHFFFAOYSA-N |
Properties
| Appearance | White Powder |
| Antibiotic Activity Spectrum | Gram-positive bacteria; Gram-negative bacteria |
| Boiling Point | 958.5 °C at 760 mmHg |
| Melting Point | 253 °C (dec.) |
| Density | 1.66 g/cm3 |
Reference Reading
1.The aminoglycoside antibiotics. I. Synthesis and biological evaluation of an analog of gentamicin.
Sitrin RD, Cooper DJ, Weisbach JA. J Antibiot (Tokyo). 1977 Oct;30(10):836-42.
The synthesis of 2-deoxy-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythrohexopyranosyl)-6-O-(3-deoxy-3-methylamino-alpha-D-xylopyranosyl)-D-streptamine (1), an analog of gentamicin A, from diideoxyneamine and methyl 3-methylamino-3-deoxy-beta-D-xylopyranoside is described. The product was characterized by its 13C nmr spectrum and was found to exhibit broad spectrum antibacterial activity.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
