(4α)-Kaurane-17,18-dioic acid
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| Category | Others |
| Catalog number | BBF-05469 |
| CAS | 58648-80-9 |
| Molecular Weight | 334.45 |
| Molecular Formula | C20H30O4 |
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Specification
| Synonyms | Kaurane-17,18-dioic acid, (4α)-; Kaurane-17,18-dioic acid, (4alpha)- |
| IUPAC Name | (4R,4aS,6aS,8S,9R,11aR,11bS)-4,11b-dimethyltetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4,8-dicarboxylic acid |
Reference Reading
1. Five new ent-kaurane diterpenes from Annona squamosa L. pericarps
Ya-Yun Chen, Cheng-Yao Ma, Mao-Lin Wang, Jia-Hui Lu, Peng Hu, Jian-Wei Chen, Xiang Li, Yong Chen Nat Prod Res. 2020 Aug;34(15):2243-2247. doi: 10.1080/14786419.2019.1582048. Epub 2019 Mar 5.
In the present study, five new ent-kaurane diterpenes including 4α-hydroxy-17,19-dinor-ent-kaurane-16-one (1), 4β-hydroxy-16β-H-18-nor-ent-kaurane-17-oic acid (2), 4β,17-dihydroxy-16α-acetoxy-18-nor-ent-kaurane (3), Annosquamosin Z (4) and 16α-H-ent-kaurane-17,18-dioic acid, 17-methy ester (5) were isolated from Annona squamosa L. pericarp. The compounds were also evaluated for their cytotoxic activities against SMMC-7721 and HepG2 cell lines, among which compound 3 exhibited potent cytotoxicity with IC50 value of less than 20 μM.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
