7-Hydro-8-methylpteroylglutamyl-glutamic acid
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category | Others |
Catalog number | BBF-00981 |
CAS | 108402-49-9 |
Molecular Weight | 586.55 |
Molecular Formula | C25H30N8O9 |
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Capabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
7-Hydro-8-methylpteroylglutamyl-glutamic acid is an antifolate produced by actinomycete SK-2049. It only has the activity against Enterococcus faecium and has no effect on other bacteria and fungi. Thymidine and folate-related compounds can counteract its activity.
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- Properties
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Synonyms | 7-Hydro-8-methylpteroylglutamyl-glutamic acid; N-(N-(4-(((2-Amino-1,4,7,8-tetrahydro-8-methyl-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-gamma-glutamyl)-L-glutamic acid; L-Glutamic acid, N-(N-(4-(((2-amino-1,4,7,8-tetrahydro-8-methyl-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-gamma-glutamyl)- |
IUPAC Name | (2S)-2-[[(4S)-4-[[4-[(2-amino-8-methyl-4-oxo-3,7-dihydropteridin-6-yl)methylamino]benzoyl]amino]-4-carboxybutanoyl]amino]pentanedioic acid |
Canonical SMILES | CN1CC(=NC2=C1N=C(NC2=O)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O |
InChI | InChI=1S/C25H30N8O9/c1-33-11-14(28-19-20(33)31-25(26)32-22(19)38)10-27-13-4-2-12(3-5-13)21(37)30-16(24(41)42)6-8-17(34)29-15(23(39)40)7-9-18(35)36/h2-5,15-16,27H,6-11H2,1H3,(H,29,34)(H,30,37)(H,35,36)(H,39,40)(H,41,42)(H3,26,31,32,38)/t15-,16-/m0/s1 |
InChI Key | VNUXXWFZEBNXLN-HOTGVXAUSA-N |
Appearance | Yellow Powder |
Antibiotic Activity Spectrum | Gram-positive bacteria |
Melting Point | >196°C(dec.) |
Density | 1.63 g/cm3 |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
