A-25822 A

Name: A-25822 A
Brand: BOC Sciences
Rating: 5 (1 reviews)

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category	Antibiotics
Catalog number	BBF-03132
CAS	50686-99-2
Molecular Weight	439.71
Molecular Formula	C30H49NO

Online Inquiry

Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

A-25822 A is an azasteroid antibiotic produced by Geotrichum flavobrienneum. It has anti-fungal activity, and the MIC for fungi such as Candida albicans, Cryptococcus neoformans, Trichophyton mentacea, Phytoplastria, Saccharomyces cerevisiae, Saccharomyces cerevisiae, Microsporum, etc. is 0.321-1.25 μg/mL. Antibacterial activity is weak.

Specification
Properties
Reference Reading
Price Product List

Synonyms	A-25822A
IUPAC Name	(1R,6aR,8S,10aS,12aR)-7,7,10a,12a-tetramethyl-1-[(2R)-6-methyl-5-methylideneheptan-2-yl]-2,3,5,6,6a,8,9,10,11,12-decahydro-1H-naphtho[1,2-h]quinolin-8-ol
Canonical SMILES	CC(C)C(=C)CCC(C)C1CCN=C2C1(CCC3=C2CCC4C3(CCC(C4(C)C)O)C)C
InChI	InChI=1S/C30H49NO/c1-19(2)20(3)9-10-21(4)23-15-18-31-27-22-11-12-25-28(5,6)26(32)14-17-29(25,7)24(22)13-16-30(23,27)8/h19,21,23,25-26,32H,3,9-18H2,1-2,4-8H3/t21-,23-,25+,26+,29-,30-/m1/s1
InChI Key	YXYIUCIRNSZNRD-JALXZWLPSA-N

Appearance	White Crystal
Antibiotic Activity Spectrum	fungi
Melting Point	147°C

1. Antifungal antibiotics from Calcarisporium thermophilum: a new source of 15-azahomosterol derivatives

P Chrisp, P M Dewick, F T Boyle Z Naturforsch C J Biosci. 1990 Mar-Apr;45(3-4):179-86. doi: 10.1515/znc-1990-3-407.

Two antifungal metabolites isolated from Calcarisporium thermophilum were identified as 15-azahomosterols related to the compounds previously isolated from Geotrichum flavo-brunneum. By full spectral comparison with authentic 15-aza-24-methylene-D-homocholesta-8,14-dien-3 beta-ol (A 25822 B) from G. flavo-brunneum, the Calcarisporium metabolites were characterized as the 4 alpha-methyl- and 4,4-dimethyl-analogues of A 25822 B. Several minor members of the series were also detected, and tentatively identified by MS analysis. The 15-azahomosterols exhibited good antifungal activity towards Candida parapsiliosis, though the activities were somewhat lower than that of the 4-demethyl derivative A25822 B. Calcarisporium thermophilum is the second microorganism known to synthesize these unusual 15-azahomosterol derivatives.

BBF-03211	AT-265	Inquiry
BBF-00703	Carminomycin I	Inquiry
BBF-02594	Pyrrolnitrin	Inquiry
BBF-01851	Fumagillin	Inquiry
BBF-00664	Alternariol	Inquiry
BBF-04624	Sulbactam Sodium	Inquiry

Bio Calculators

Solution Dilution Calculator
Molecular Weight Calculator
Molarity Calculator

Stock concentration: *

Desired final volume: *

Desired concentration: *

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C₁V₁ = C₂V₂

Calculate

* Total Molecular Weight:

g/mol

Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳

Formula weight: *

g/mol

Desired final volume: *

Desired concentration: *

Online Inquiry

*Name:

*Phone:

*Email:

*Quantity:

*Service & Products Interested:

Project Description:

A-25822 A

Capabilities & Facilities

Product Description

Bio Calculators

Recently viewed products

Online Inquiry