A-500359D
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Category | Antibiotics |
Catalog number | BBF-03175 |
CAS | 254449-22-4 |
Molecular Weight | 567.54 |
Molecular Formula | C24H33N5O11 |
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Description
A-500359D is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 µg/mL.
Specification
IUPAC Name | (2S,4R)-2-[(1S)-2-amino-1-[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-3-methoxyoxolan-2-yl]-2-oxoethoxy]-4-hydroxy-N-[(3S,7R)-7-methyl-2-oxoazepan-3-yl]-3,4-dihydro-2H-pyran-6-carboxamide |
Canonical SMILES | CC1CCCC(C(=O)N1)NC(=O)C2=CC(CC(O2)OC(C3C(C(C(O3)N4C=CC(=O)NC4=O)O)OC)C(=O)N)O |
InChI | InChI=1S/C24H33N5O11/c1-10-4-3-5-12(21(34)26-10)27-22(35)13-8-11(30)9-15(38-13)39-19(20(25)33)18-17(37-2)16(32)23(40-18)29-7-6-14(31)28-24(29)36/h6-8,10-12,15-19,23,30,32H,3-5,9H2,1-2H3,(H2,25,33)(H,26,34)(H,27,35)(H,28,31,36)/t10-,11+,12+,15-,16-,17+,18+,19+,23-/m1/s1 |
InChI Key | KMZLQNUZDFXWBQ-OZZUZIEOSA-N |
Properties
Appearance | Powder |
Antibiotic Activity Spectrum | Gram-positive bacteria; mycobacteria |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2