A-500359H
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Category | Antibiotics |
Catalog number | BBF-03179 |
CAS | |
Molecular Weight | 445.33 |
Molecular Formula | C16H19N3O12 |
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Description
A-500359H is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 µg/mL.
Specification
IUPAC Name | (2S,3S,4S)-2-[(1S)-2-amino-1-[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]-2-oxoethoxy]-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid |
Canonical SMILES | C1=CN(C(=O)NC1=O)C2C(C(C(O2)C(C(=O)N)OC3C(C(C=C(O3)C(=O)O)O)O)O)O |
InChI | InChI=1S/C16H19N3O12/c17-12(25)11(31-15-7(22)4(20)3-5(29-15)14(26)27)10-8(23)9(24)13(30-10)19-2-1-6(21)18-16(19)28/h1-4,7-11,13,15,20,22-24H,(H2,17,25)(H,26,27)(H,18,21,28)/t4-,7-,8-,9+,10-,11-,13+,15+/m0/s1 |
InChI Key | IHFPUFPCUYMJRS-ZEDZFBBQSA-N |
Properties
Antibiotic Activity Spectrum | Gram-positive bacteria; mycobacteria |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2