Acivicin
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category | Enzyme inhibitors |
Catalog number | BBF-00541 |
CAS | 42228-92-2 |
Molecular Weight | 178.57 |
Molecular Formula | C5H7ClN2O3 |
Purity | ≥98% by HPLC |
Online Inquiry
Capabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
Acivicin is an isoxazole antibiotic isolated from Streptomyces. sviceus. Acivicin is a glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and 560 μM for anthranilate synthase and glutamate synthase, respectively) as a potent antitumor antibiotic that induces apoptosis in human lymphoblastoid cells. Acivicin is an inhibitor of GGT used for solid tumor research
- Specification
- Properties
- Reference Reading
- Price Product List
Synonyms | (S-(R*,R*))-4,5-Dihydro-alpha-amino-3-chloro-5-isoxazoleacetic acid; (alpha-S,5S)-alpha-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid; (alphaS,5S)-alpha-Amino-3-chlor-4,5-dihydro-5-isoxazolylessigsaeure |
Shelf Life | As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly. |
Storage | Store at -20°C |
IUPAC Name | (2S)-2-amino-2-[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]acetic acid |
Canonical SMILES | C1C(ON=C1Cl)C(C(=O)O)N |
InChI | InChI=1S/C5H7ClN2O3/c6-3-1-2(11-8-3)4(7)5(9)10/h2,4H,1,7H2,(H,9,10)/t2-,4-/m0/s1 |
InChI Key | QAWIHIJWNYOLBE-OKKQSCSOSA-N |
Appearance | White to Beige Powder |
Application | Protease inhibitor |
Boiling Point | 341.6°C at 760 mmHg |
Melting Point | 228-230 °C |
Density | 1.85 g/cm3 |
Solubility | Soluble in DMSO |
BBF-04727 | Strigolactone GR24 | Inquiry |
BBF-04301 | Tulathromycin A | Inquiry |
BBF-00968 | Homoalanosine | Inquiry |
BBF-05880 | N-Me-L-Ala-maytansinol | Inquiry |
BBF-03753 | Baicalin | Inquiry |
BBF-05886 | Notoginsenoside R1 | Inquiry |
Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
