Metabolites-BOC Sciences


Actiketal - CAS 133658-47-6

Catalog number: BBF-00024

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Catalog Number BBF-00024
CAS 133658-47-6
Description Actiketal is a glutarimide antibiotic isolated from Streptomyces pulveraceus subsp. epiderstagenes. Actiketal can inhibit the incorporation of [3H] thymidine into Balb/MB cells activated by epidermal growth factor, with IC50 of 14.5 µmol/L, which is stronger than its analog Actiphenol (109.6 µmol/L), but better than epidermal statin (Epiderstatin) 3000 times weaker.
Molecular Formula C15H15NO5
Molecular Weight 289.28
IUPAC Name 4-(2-hydroxy-5,7-dimethyl-3-oxo-1-benzofuran-2-yl)piperidine-2,6-dione
Canonical SMILES CC1=CC(=C2C(=C1)C(=O)C(O2)(C3CC(=O)NC(=O)C3)O)C
InChI InChI=1S/C15H15NO5/c1-7-3-8(2)13-10(4-7)14(19)15(20,21-13)9-5-11(17)16-12(18)6-9/h3-4,9,20H,5-6H2,1-2H3,(H,16,17,18)
Boiling Point 584.9°C at 760 mmHg
Melting Point 96-100°C
Density 1.423 g/cm3
Appearance White Powder
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