Actinopyrone B
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| Category | Antibiotics |
| Catalog number | BBF-00546 |
| CAS | 88378-60-3 |
| Molecular Weight | 386.52 |
| Molecular Formula | C24H34O4 |
| Purity | 95% |
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Description
Actinopyrone B is an antibiotic isolated from Streptomyces pacttm. Actinopyrone has a relaxing effect on the coronary blood vessels of anesthetized dogs, and has weak anti-gram-positive bacteria and trichoderma activity.
Specification
| Synonyms | 4H-Pyran-4-one, 2-(10-hydroxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraenyl)-6-methoxy-3-methyl- |
| IUPAC Name | 2-[(2E,5E,7E,11E)-10-hydroxy-3,7,9,11-tetramethyltrideca-2,5,7,11-tetraenyl]-6-methoxy-3-methylpyran-4-one |
| Canonical SMILES | CC=C(C)C(C(C)C=C(C)C=CCC(=CCC1=C(C(=O)C=C(O1)OC)C)C)O |
| InChI | InChI=1S/C24H34O4/c1-8-18(4)24(26)19(5)14-17(3)11-9-10-16(2)12-13-22-20(6)21(25)15-23(27-7)28-22/h8-9,11-12,14-15,19,24,26H,10,13H2,1-7H3/b11-9+,16-12+,17-14+,18-8+ |
| InChI Key | VKAOERDMNZUNBK-AUTRRBDOSA-N |
Properties
| Appearance | Colorless Oil |
| Antibiotic Activity Spectrum | Gram-positive bacteria; fungi |
Reference Reading
1. Actinopyrones A, B and C, new physiologically active substances. II. Physico-chemical properties and chemical structures
K Yano, K Yokoi, J Sato, J Oono, T Kouda, Y Ogawa, T Nakashima J Antibiot (Tokyo). 1986 Jan;39(1):38-43. doi: 10.7164/antibiotics.39.38.
The structure of physiologically active substances, actinopyrones A, B and C, produced by Streptomyces pactum S12538 were determined on the basis of their spectral and chemical character. These substances were structurally related to piericidin A1.
2. Actinopyrones A, B and C, new physiologically active substances. I. Producing organism, fermentation, isolation and biological properties
K Yano, K Yokoi, J Sato, J Oono, T Kouda, Y Ogawa, T Nakashima J Antibiot (Tokyo). 1986 Jan;39(1):32-7. doi: 10.7164/antibiotics.39.32.
A strain of Streptomyces was found to produce new physiologically active substances. The active compounds were purified and separated into three substances named actinopyrones A, B and C. Actinopyrones exhibited coronary vasodilating activities in anesthetized dogs and weakly antimicrobial activities against some Gram-positive bacteria and dermatophytes.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
