Aggreceride A
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Enzyme inhibitors |
| Catalog number | BBF-00388 |
| CAS | 19207-26-2 |
| Molecular Weight | 316.47 |
| Molecular Formula | C18H36O4 |
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Description
It is produced by the strain of Streptomyces sp. OM-3209. Aggreceride had no antibacterial activity. Aggreceride A of 50 ㎍/ml inhibited thrombin-induced platelet aggregation of 92%. Aggreceride A of 25 ㎍/ml inhibited thrombin-induced platelet aggregation of 81%.
Specification
| Synonyms | S3L0ID00Y9; 2,3-Dihydroxypropyl 12-methyltetradecanoate; Tetradecanoic acid, 12-methyl-, 2,3-dihydroxypropyl ester; CTK4E0886; DTXSID50172766; (S)-12-Methyltetradecanoic acid (R)-2,3-dihydroxypropyl ester; Tetradecanoic acid,12-methyl-, (2R)-2,3-dihydroxypropyl ester, (12S)- |
| IUPAC Name | [(2R)-2,3-dihydroxypropyl] (12S)-12-methyltetradecanoate |
| Canonical SMILES | CCC(C)CCCCCCCCCCC(=O)OCC(CO)O |
| InChI | InChI=1S/C18H36O4/c1-3-16(2)12-10-8-6-4-5-7-9-11-13-18(21)22-15-17(20)14-19/h16-17,19-20H,3-15H2,1-2H3/t16-,17+/m0/s1 |
| InChI Key | HLQJYDUSPITBCP-DLBZAZTESA-N |
Properties
| Appearance | White Amorphous Powder |
| Boiling Point | 433.7 °C at 760 mmHg |
| Density | 0.974 g/cm3 |
| Solubility | Soluble in Chloroform |
Reference Reading
1. Synthesis of both the enantiomers of aseanostatin P5 (sarcinic acid), an inhibitor of myeloperoxidase release, and four diastereomers of aggreceride A, a platelet aggregation inhibitor
T Kitahara, S Aono, K Mori Biosci Biotechnol Biochem. 1995 Jan;59(1):78-82. doi: 10.1271/bbb.59.78.
Both the enantiomers of aseanostatin P5 (sarcinic acid), an inhibitor of myeloperoxidase (MPO) release from human polymorphonuclear leukocytes (PMN), with high optical purity were synthesized by starting from (S)-2-methylbutanol and methyl (S)-3-hydroxy-2-methylpropanoate. They were converted to four diastereomers of aggreceride A, a platelet aggregation inhibitor.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
