Albendazole
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Others |
| Catalog number | BBF-03783 |
| CAS | 54965-21-8 |
| Molecular Weight | 265.33 |
| Molecular Formula | C12H15N3O2S |
| Purity | 98% by HPLC |
Online Inquiry
Capabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
Albendazole is an anthelmintic. It prevents the enzymatic process that causes the parasite to absorb glucose, leading to its death.
- Specification
- Properties
- Toxicity
- Reference Reading
- Spectrum
- Price Product List
| Synonyms | SKF-62979; SKF 62979; SKF62979; Eskazole; Zentel; Albenza; Valbazen |
| Storage | Store at -20°C (dark) |
| IUPAC Name | methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate |
| Canonical SMILES | CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC |
| InChI | InChI=1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16) |
| InChI Key | HXHWSAZORRCQMX-UHFFFAOYSA-N |
| Source | Synthetic |
| Appearance | White to Off-white Solid |
| Application | Mesh headings: anthelmintics, Anticestodalagents, Antiprotozoal agents |
| Antibiotic Activity Spectrum | parasites |
| Melting Point | 193-198°C |
| Density | 1.3±0.1 g/cm3 |
| Solubility | Soluble in acetic acid, chloroform |
| LogP | 2.7 |
| Carcinogenicity | No indication of carcinogenicity to humans (not listed by IARC). |
| Mechanism Of Toxicity | Albendazole causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their glycogen stores. Degenerative changes in the endoplasmic reticulum, the mitochondria of the germinal layer, and the subsequent release of lysosomes result in decreased production of adenosine triphosphate (ATP), which is the energy required for the survival of the helminth. Due to diminished energy production, the parasite is immobilized and eventually dies. |
| Toxicity | LD50: 1500 mg/kg (oral,mouse). |
Spectrum
GC-MS Spectrum - GC-EI-TOF (Non-derivatized)
Experimental Conditions
Ionization Mode: positive
Chromatography Type: GC
Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive
Experimental Conditions
Ionization Energy: 70 eV
Chromatography Type: Gas Chromatography Column (GC)
Instrument Type: Single quadrupole, spectrum predicted by CFM-ID(EI)
Mass Resolution: 0.0001 Da
Molecular Formula: C12H15N3O2S
Molecular Weight (Monoisotopic Mass): 265.0885 Da
Molecular Weight (Avergae Mass): 265.331 Da
LC-MS/MS Spectrum - LC-ESI-QFT , negative
Experimental Conditions
Ionization Mode: negative
Predicted LC-MS/MS Spectrum - 10V, Positive
Experimental Conditions
Collision Energy: 10 eV
Instrument Type: QTOF (generic), spectrum predicted by CFM-ID
Mass Resolution: 0.0001 Da
Molecular Formula: C12H15N3O2S
Molecular Weight (Monoisotopic Mass): 265.0885 Da
Molecular Weight (Avergae Mass): 265.331 Da
1H NMR Spectrum
Experimental Conditions
Instrument Type: JEOL
Nucleus: 1H
Frequency: 400 MHz
Chemical Shift Reference: TMS
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
