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Amodiaquin dihydrochloride dihydrate

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Amodiaquin dihydrochloride dihydrate
Category Enzyme inhibitors
Catalog number BBF-03926
CAS 6398-98-7
Molecular Weight 464.81
Molecular Formula C20H28Cl3N3O3
Purity >98%

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Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

Amodiaquine, a 4-aminoquinoquinoline compound, is a histamine N-methyltransferase inhibitor, used as an antimalarial and anti-inflammatory agent for more than 40 years.

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Related CAS 86-42-0 (free base)
Synonyms AMODIAQUIN DIHYDROCHLORIDE; amodiaquin dihydrochloride dihydrate; AMODIAQUINE DIHYDROCHLORIDE; AMODIAQUINE HCL; AMODIAQUIN HYDROCHLORIDE; 4-[(7-CHLORO-4-QUINOLINYL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL DIHYDROCHLORIDE; 4-([7-chloro-4-quinolinyl]amino)-2-([diet
Shelf Life As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Storage Store at -20°C
IUPAC Name 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol;dihydrate;dihydrochloride
Canonical SMILES CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O.O.O.Cl.Cl
InChI InChI=1S/C20H22ClN3O.2ClH.2H2O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19;;;;/h5-12,25H,3-4,13H2,1-2H3,(H,22,23);2*1H;2*1H2
InChI Key YVNAYSHNIILOJS-UHFFFAOYSA-N
Source Synthetic
Appearance Light Yellow to Yellow Solid
Application Antimalarial
Melting Point >197°C (dec.)
Solubility Soluble in DMSO
1.The antifertility effect of amodiaquine hydrochloride.
Gbotolorun SC1, Osinubi AA, Oremosu AA, Noronha CC. Nig Q J Hosp Med. 2011 Oct-Dec;21(4):271-5.
BACKGROUND: A number of antimalarial compounds and herbs have been reported to possess antifertility actions. Amodiaquine (AQ) belongs to the same class of drugs as chloroquine. Chloroquine has been reported to disrupt the oestrus cycle, block ovulation and consequently reduce fertility.

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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