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Amycin B

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Category Antibiotics
Catalog number BBF-00454
CAS 129313-99-1
Molecular Weight 1056.41
Molecular Formula C56H101N3O15

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Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

It is produced by the strain of Streptomyces sp. DSM 3816. It has the activity of anti-ringworm, microspora, candida, aspergillus and other fungi and gram-positive bacteria such as staphylococcus and streptococcus.

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Synonyms Scopafungin, 23-O-de(carboxyacetyl)-8,47-didemethyl-14,49-dimethyl-
IUPAC Name 1-[(E)-11-(3,5,7,9,19,23,25,27,31,33,34,35-dodecahydroxy-8,14,18,22,26,30-hexamethyl-17-oxo-16,37-dioxabicyclo[31.3.1]heptatriaconta-10,12,20-trien-15-yl)-9-methyldodec-4-enyl]-2-methylguanidine
Canonical SMILES CC1CCC(C(C(CC(C(C=CC(C(C(=O)OC(C(C=CC=CC(C(C(CC(CC(CC2CC(C(C(O2)(CC1O)O)O)O)O)O)O)C)O)C)C(C)CC(C)CCCC=CCCCNC(=NC)N)C)O)C)O)O)C)O
InChI InChI=1S/C56H101N3O15/c1-33(18-14-12-10-11-13-17-25-59-55(57)58-9)26-37(5)52-36(4)19-15-16-20-44(62)38(6)48(66)29-42(61)27-41(60)28-43-30-50(68)53(70)56(72,74-43)32-51(69)35(3)22-23-45(63)39(7)49(67)31-47(65)34(2)21-24-46(64)40(8)54(71)73-52/h10-11,15-16,19-21,24,33-53,60-70,72H,12-14,17-18,22-23,25-32H2,1-9H3,(H3,57,58,59)/b11-10+,19-15?,20-16?,24-21?
InChI Key PPUSZMZQPGFMIJ-HURQSWDASA-N
Antibiotic Activity Spectrum Gram-positive bacteria
Boiling Point 1134.0 °C at 760 mmHg
Density 1.230 g/cm3
Solubility Soluble in Methanol
1. Secondary metabolites by chemical screening: II. Amycins A and B two novel niphimycin analogs isolated from a high producer strain of elaiophylin and nigericin
S Grabley, P Hammann, W Raether, J Wink, A Zeeck J Antibiot (Tokyo). 1990 Jun;43(6):639-47. doi: 10.7164/antibiotics.43.639.
Two novel natural niphimycin analogs, amycins A (5) and B (3) were isolated from the culture broth of the Streptomyces sp. DSM 3816 by chemical screening methods. In addition this strain produces the antibiotics niphimycin (4), elaiophylin (2) and nigericin (1). Fermentation, isolation, structure elucidation and biological activity of the amycins are described.

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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