Amycin B
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| Category | Antibiotics |
| Catalog number | BBF-00454 |
| CAS | 129313-99-1 |
| Molecular Weight | 1056.41 |
| Molecular Formula | C56H101N3O15 |
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Description
It is produced by the strain of Streptomyces sp. DSM 3816. It has the activity of anti-ringworm, microspora, candida, aspergillus and other fungi and gram-positive bacteria such as staphylococcus and streptococcus.
Specification
| Synonyms | Scopafungin, 23-O-de(carboxyacetyl)-8,47-didemethyl-14,49-dimethyl- |
| IUPAC Name | 1-[(E)-11-(3,5,7,9,19,23,25,27,31,33,34,35-dodecahydroxy-8,14,18,22,26,30-hexamethyl-17-oxo-16,37-dioxabicyclo[31.3.1]heptatriaconta-10,12,20-trien-15-yl)-9-methyldodec-4-enyl]-2-methylguanidine |
| Canonical SMILES | CC1CCC(C(C(CC(C(C=CC(C(C(=O)OC(C(C=CC=CC(C(C(CC(CC(CC2CC(C(C(O2)(CC1O)O)O)O)O)O)O)C)O)C)C(C)CC(C)CCCC=CCCCNC(=NC)N)C)O)C)O)O)C)O |
| InChI | InChI=1S/C56H101N3O15/c1-33(18-14-12-10-11-13-17-25-59-55(57)58-9)26-37(5)52-36(4)19-15-16-20-44(62)38(6)48(66)29-42(61)27-41(60)28-43-30-50(68)53(70)56(72,74-43)32-51(69)35(3)22-23-45(63)39(7)49(67)31-47(65)34(2)21-24-46(64)40(8)54(71)73-52/h10-11,15-16,19-21,24,33-53,60-70,72H,12-14,17-18,22-23,25-32H2,1-9H3,(H3,57,58,59)/b11-10+,19-15?,20-16?,24-21? |
| InChI Key | PPUSZMZQPGFMIJ-HURQSWDASA-N |
Properties
| Antibiotic Activity Spectrum | Gram-positive bacteria |
| Boiling Point | 1134.0 °C at 760 mmHg |
| Density | 1.230 g/cm3 |
| Solubility | Soluble in Methanol |
Reference Reading
1. Secondary metabolites by chemical screening: II. Amycins A and B two novel niphimycin analogs isolated from a high producer strain of elaiophylin and nigericin
S Grabley, P Hammann, W Raether, J Wink, A Zeeck J Antibiot (Tokyo). 1990 Jun;43(6):639-47. doi: 10.7164/antibiotics.43.639.
Two novel natural niphimycin analogs, amycins A (5) and B (3) were isolated from the culture broth of the Streptomyces sp. DSM 3816 by chemical screening methods. In addition this strain produces the antibiotics niphimycin (4), elaiophylin (2) and nigericin (1). Fermentation, isolation, structure elucidation and biological activity of the amycins are described.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
