Anguinomycin B

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Category Antibiotics
Catalog number BBF-00471
CAS 111278-00-3
Molecular Weight 526.70
Molecular Formula C32H46O6

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Description

It is produced by the strain of Streptomyces sp. R2827 and R2827-2. It has anti-mouse Lewis lung cancer and P388 leukemia activity, and in vivo test shows that B has a strong anti-cancer effect on mouse solid cancer. It has been reported that it can stop normal cell growth and cause deformable cell death.

Specification

Synonyms KR-2827A; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-
IUPAC Name (2E,10E,12E,16E,18E)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-19-(6-oxo-2,3-dihydropyran-2-yl)nonadeca-2,10,12,16,18-pentaenoic acid
Canonical SMILES CCC(=CC(C)CC=CC(=CC(C)C(=O)C(C)C(C(C)CC(=CC(=O)O)C)O)C)C=CC1CC=CC(=O)O1
InChI InChI=1S/C32H46O6/c1-8-27(15-16-28-13-10-14-30(35)38-28)19-22(3)12-9-11-21(2)17-24(5)31(36)26(7)32(37)25(6)18-23(4)20-29(33)34/h9-11,14-17,19-20,22,24-26,28,32,37H,8,12-13,18H2,1-7H3,(H,33,34)/b11-9+,16-15+,21-17+,23-20+,27-19+
InChI Key QLEZOSIKJQCEQI-MVGWMUTRSA-N

Properties

Appearance Colorless Oily Matter
Antibiotic Activity Spectrum neoplastics (Tumor)
Boiling Point 722.8 °C at 760 mmHg
Density 1.087 g/cm3
Solubility Soluble in Methanol

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