Antibiotic 66-40G

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Category Antibiotics
Catalog number BBF-02995
CAS 66762-58-1
Molecular Weight 433.50
Molecular Formula C18H35N5O7

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Description

It is produced by the strain of Micromonospora inyoensis. It has activity against gram-positive and gram-negative bacteria.

Specification

Synonyms 3''-N-demethyl-sisomicin
IUPAC Name (2R,3R,4R,5R)-4-amino-2-(((1S,2S,3R,4S,6R)-4,6-diamino-3-(((2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-5-methyltetrahydro-2H-pyran-3,5-diol

Properties

Appearance White Powder
Antibiotic Activity Spectrum Gram-positive bacteria; Gram-negative bacteria
Melting Point 168-178°C
Solubility Soluble in Water

Reference Reading

1. The structure of aminoglycoside antibiotic 66-40G produced by Micromonospora inyoensis
M Kugelman, R S Jaret, S Mittelman, W Gau J Antibiot (Tokyo). 1978 Jul;31(7):643-5. doi: 10.7164/antibiotics.31.643.
Aminoglycoside antibiotic 66-40G is a minor component produced in the fermentation of Micromonospora inyoensis. Its structure has been established as 3''-de-N-methyl-sisomicin (4) by spectroscopic means and by direct comparison with an authentic sample obtained from photochemical oxidative de-N-methylation of sisomicin (1).

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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