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Antibiotic 834-B1

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Category Antibiotics
Catalog number BBF-03006
CAS 95261-51-1
Molecular Weight 224.32
Molecular Formula C12H16O2S

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Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

It is an antibiotic produced by the strain of Streptomyces Y-0834H. Its activity against Psudomonas aeruginosa NCTC 10490 is stronger than Thiolactomycin, but lower than Thiotetromycin.

  • Specification
  • Properties
  • Reference Reading
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Synonyms 834-B1; 2(5H)-Thiophenone, 5-ethyl-4-hydroxy-3-methyl-5-(2-methyl-1,3-butadienyl)-; Antibiotic Y 0834B1
IUPAC Name 5-ethyl-4-hydroxy-3-methyl-5-(2-methylbuta-1,3-dienyl)thiophen-2-one
Canonical SMILES CCC1(C(=C(C(=O)S1)C)O)C=C(C)C=C
InChI InChI=1S/C12H16O2S/c1-5-8(3)7-12(6-2)10(13)9(4)11(14)15-12/h5,7,13H,1,6H2,2-4H3
InChI Key HBYOKPONWLKKRI-UHFFFAOYSA-N
Antibiotic Activity Spectrum Gram-negative bacteria
Boiling Point 334.4°C at 760 mmHg
Density 1.176 g/cm3
Solubility Soluble in Methanol
1. 834-B1, a new thiolactone containing antibiotic taxonomy, fermentation, isolation and structure
T Sato, K Suzuki, S Kadota, K Abe, S Takamura, M Iwanami J Antibiot (Tokyo). 1989 Jun;42(6):890-6. doi: 10.7164/antibiotics.42.890.
A new thiolactone containing antibiotic 834-B1 was isolated from the culture broth of Streptomyces sp. Y-0834H which has also produced thiolactomycin and thiotetromycin at the same time. The structure of 834-B1 was determined as I by the decoupling experiment in NMR.

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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