Antibiotic 834-B1
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| Category | Antibiotics |
| Catalog number | BBF-03006 |
| CAS | 95261-51-1 |
| Molecular Weight | 224.32 |
| Molecular Formula | C12H16O2S |
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Description
It is an antibiotic produced by the strain of Streptomyces Y-0834H. Its activity against Psudomonas aeruginosa NCTC 10490 is stronger than Thiolactomycin, but lower than Thiotetromycin.
Specification
| Synonyms | 834-B1; 2(5H)-Thiophenone, 5-ethyl-4-hydroxy-3-methyl-5-(2-methyl-1,3-butadienyl)-; Antibiotic Y 0834B1 |
| IUPAC Name | 5-ethyl-4-hydroxy-3-methyl-5-(2-methylbuta-1,3-dienyl)thiophen-2-one |
| Canonical SMILES | CCC1(C(=C(C(=O)S1)C)O)C=C(C)C=C |
| InChI | InChI=1S/C12H16O2S/c1-5-8(3)7-12(6-2)10(13)9(4)11(14)15-12/h5,7,13H,1,6H2,2-4H3 |
| InChI Key | HBYOKPONWLKKRI-UHFFFAOYSA-N |
Properties
| Antibiotic Activity Spectrum | Gram-negative bacteria |
| Boiling Point | 334.4°C at 760 mmHg |
| Density | 1.176 g/cm3 |
| Solubility | Soluble in Methanol |
Reference Reading
1. 834-B1, a new thiolactone containing antibiotic taxonomy, fermentation, isolation and structure
T Sato, K Suzuki, S Kadota, K Abe, S Takamura, M Iwanami J Antibiot (Tokyo). 1989 Jun;42(6):890-6. doi: 10.7164/antibiotics.42.890.
A new thiolactone containing antibiotic 834-B1 was isolated from the culture broth of Streptomyces sp. Y-0834H which has also produced thiolactomycin and thiotetromycin at the same time. The structure of 834-B1 was determined as I by the decoupling experiment in NMR.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
