Aphidicolin
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category | Antibiotics |
Catalog number | BBF-00556 |
CAS | 38966-21-1 |
Molecular Weight | 338.48 |
Molecular Formula | C20H34O4 |
Purity | >98% |
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Capabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
Aphidicolin is an antibiotic produced by Cephalosporium aphidicola and Nigrospora sphaerica, which has the effect of inhibiting mitosis and anti-DNA virus. Aphidicolin potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line.
- Specification
- Properties
- Reference Reading
- Price Product List
Synonyms | (+)-Aphidicolin; (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol |
Shelf Life | As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly. |
Storage | Store at -20°C |
IUPAC Name | (1S,2S,5R,6R,7R,10S,12R,13R)-6,13-bis(hydroxymethyl)-2,6-dimethyltetracyclo[10.3.1.01,10.02,7]hexadecane-5,13-diol |
Canonical SMILES | CC12CCC(C(C1CCC3C24CCC(C(C3)C4)(CO)O)(C)CO)O |
InChI | InChI=1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1 |
InChI Key | NOFOAYPPHIUXJR-APNQCZIXSA-N |
Source | Nigrospora oryzae |
Appearance | White to Off-white Powder |
Application | A reversible inhibitor of eukaryotic nuclear DNA replication |
Antibiotic Activity Spectrum | viruses |
Boiling Point | 507.8°C at 760 mmHg |
Melting Point | 225-233°C |
Flash Point | 230.4±24.7 °C |
Density | 1.22 g/cm3 |
Solubility | Soluble in DMSO |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
