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Aristeromycin

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Aristeromycin
Category Antibiotics
Catalog number BBF-00561
CAS 19186-33-5
Molecular Weight 265.27
Molecular Formula C11H15N5O3

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Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

Aristeromycin is a nucleoside antibiotic produced by Streptomyces citricolor. It has a minimum inhibitory concentration of 5 mg/mL against Xanthomonas oryzae and Pear.

  • Specification
  • Properties
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Synonyms Cycloadenosine; (1R,2S,3R,5R)-3-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol
IUPAC Name (1R,2S,3R,5R)-3-(6-aminopurin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol
Canonical SMILES C1C(C(C(C1N2C=NC3=C(N=CN=C32)N)O)O)CO
InChI InChI=1S/C11H15N5O3/c12-10-7-11(14-3-13-10)16(4-15-7)6-1-5(2-17)8(18)9(6)19/h3-6,8-9,17-19H,1-2H2,(H2,12,13,14)/t5-,6-,8-,9+/m1/s1
InChI Key UGRNVLGKAGREKS-GCXDCGAKSA-N
Appearance Colorless Prismatic Crystal
Antibiotic Activity Spectrum fungi
Boiling Point 595.1°C at 760 mmHg
Melting Point 213-215°C (dec.)
Density 1.92 g/cm3
Solubility Soluble in Acetic acid, Water, Methanol
1.The 5'-nor aristeromycin analogues of 5'-deoxy-5'-methylthioadenosine and 5'-deoxy-5'-thiophenyladenosine.
Das SR1, Schneller SW. Nucleosides Nucleotides Nucleic Acids. 2014;33(10):668-77. doi: 10.1080/15257770.2014.917671.
To extend the potential of 5'-noraristeromycin (and its enantiomer) as potential antiviral candidates, the enantiomers of the carbocyclic 5'-nor derivatives of 5'-methylthio-5'-deoxyadenosine and 5'-phenylthio-5'-deoxyadenosine have been synthesized and evaluated. None of the compounds showed meaningful antiviral activity.

Bio Calculators

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
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